Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 9/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | CMA1 | P23946 | 2/20 | 0.32 |
| ▸ | AHR | P35869 | 2/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL548762 | 0.74 | AHR (0.50) | PGRCMA1AHREIF2AK2KIF11 | |
| SCHEMBL4104017 | 0.72 | CA9 (0.52) | CA9KDM4EKMT2ASMN1; SMN2KIF11 | |
| SCHEMBL3764909 | 0.69 | AHR (0.38) | DPP4CA9PGRCMA1AHR | |
| SCHEMBL22469472 | 0.69 | MAPT (0.52) | CA9MEN1RAB9AKMT2AKIF11 | |
| SCHEMBL30937518 | 0.65 | DPP4 (0.38) | DPP4KDM4EMEN1ALDH1A1RAB9A | |
| SCHEMBL153758 | 0.64 | HDAC3 (0.46) | CA9PGRCMA1AHREIF2AK2 | |
| SCHEMBL31727396 | 0.64 | HDAC3 (0.46) | CA9PGRCMA1AHREIF2AK2 | |
| SCHEMBL21646067 | 0.63 | CA9 (0.54) | CA9KDM4EALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL14361898 | 0.62 | CYP11B1 (0.42) | PGRCMA1AHRHTR2C | |
| SCHEMBL1847559 | 0.61 | AHR (0.53) | PGRCMA1AHREIF2AK2KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2250157-B1 | NOVEL HETEROCYCLIC COMPOUNDS | PANACEA BIOTEC LTD (IN) | 2014-11-05 | — | — | EP | disclosed |