SCHEMBL16216009

SCHEMBL16216009

CCCCCCCCCCCCCCCCNC(=O)CCNC(=O)C(O)C(C)(C)COP(=O)(O)OP(=O)(O)OCC1OC(n2cnc3c(N)ncnc32)C(O)C1OP(=O)(O)O

nearest known ligand 0.86

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
EP300 Q09472 4/20 0.86
CHAT P28329 2/20 0.86
NAA50 Q9GZZ1 2/20 0.86
AURKA O14965 2/20 0.86
KAT5 Q92993 2/20 0.86
KAT2B Q92831 1/20 0.86
CREBBP Q92793 1/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16216000 1.00 EP300 (0.86) EP300CHATNAA50AURKAKAT5
SCHEMBL18179672 0.98 EP300 (0.89) EP300CHATNAA50AURKAKAT5
SCHEMBL14124861 0.95 EP300 (0.85) EP300CHATNAA50AURKAKAT5
SCHEMBL12040594 0.95 EP300 (0.91) EP300CHATNAA50AURKAKAT5
SCHEMBL13948493 0.95 EP300 (0.91) EP300CHATNAA50AURKAKAT5
SCHEMBL14769749 0.95 EP300 (0.86) EP300CHATNAA50AURKAKAT5
SCHEMBL31183059 0.94 CHAT (0.81) EP300CHATNAA50AURKAKAT5
SCHEMBL30619604 0.94 CHAT (0.81) EP300CHATNAA50AURKAKAT5
SCHEMBL29876653 0.94 CHAT (0.81) EP300CHATNAA50AURKAKAT5
SCHEMBL26165784 0.94 EP300 (0.88) EP300CHATNAA50AURKAKAT5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140330246-A1 Intrauterine fetal growth restriction - The biochemical rationale of treatment modalities including extraperitoneal transamniotic fetal supplements PATURU SUMATHI (US) 2014-11-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140330246-A1 Intrauterine fetal growth restriction - The biochemical rationale of treatment modalities including extraperitoneal transamniotic fetal supplements ALPP, SLC2A1, SLC2A2 EP300 639/4885CHAT 518/4885NAA50 1086/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.