Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 3/20 | 0.50 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.45 |
| ▸ | TYMS | P04818 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KRAS | P01116 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.39 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.38 |
| ▸ | TK2 | O00142 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2953389 | 1.00 | TK1 (0.50) | TK1SLC29A1TYMSLMNASMN1; SMN2 | |
| SCHEMBL14395733 | 0.88 | SLC29A1 (0.45) | TK1SLC29A1TYMSLMNASMN1; SMN2 | |
| SCHEMBL13264893 | 0.87 | SLC29A1 (0.45) | TK1SLC29A1TYMSLMNASMN1; SMN2 | |
| SCHEMBL14395965 | 0.87 | TK1 (0.46) | TK1SLC29A1TYMSLMNASMN1; SMN2 | |
| SCHEMBL16217253 | 0.85 | SLC29A1 (0.43) | TK1SLC29A1TYMSLMNASMN1; SMN2 | |
| SCHEMBL16220659 | 0.85 | SLC29A1 (0.43) | TK1SLC29A1TYMSLMNASMN1; SMN2 | |
| SCHEMBL19113318 | 0.82 | SLC29A1 (0.43) | TK1SLC29A1TYMSLMNASMN1; SMN2 | |
| SCHEMBL16217252 | 0.82 | SLC29A1 (0.43) | TK1SLC29A1TYMSLMNASMN1; SMN2 | |
| SCHEMBL16220654 | 0.81 | TK1 (0.52) | TK1TYMSLMNASMN1; SMN2CYP1A2 | |
| SCHEMBL12732344 | 0.80 | SLC29A1 (0.47) | TK1SLC29A1TYMSLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9988680-B2 | Non-natural nucleosides as theranostic agents | CASE WESTERN RESERVE UNIVERSITY (US) | 2018-06-05 | — | — | US | disclosed |
| US-20140329236-A1 | NON-NATURAL NUCLEOSIDES AS THERANOSTIC AGENTS | CASE WESTERN RESERVE UNIVERSITY | 2014-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140329236-A1 | NON-NATURAL NUCLEOSIDES AS THERANOSTIC AGENTS | TYMP, TYMS, UNG | TK1 24/4885SLC29A1 50/4885TYMS 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.