⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31737638 | 0.79 | — | — | |
| SCHEMBL15743726 | 0.79 | — | — | |
| SCHEMBL6628886 | 0.79 | — | — | |
| SCHEMBL15744076 | 0.79 | — | — | |
| SCHEMBL20016966 | 0.79 | — | — | |
| SCHEMBL21230409 | 0.79 | — | — | |
| SCHEMBL14535578 | 0.73 | — | — | |
| SCHEMBL25692479 | 0.73 | — | — | |
| SCHEMBL18747365 | 0.71 | — | — | |
| SCHEMBL27643029 | 0.71 | ENGASE (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9051326-B2 | Pyrazoline derivatives and their use as selective androgen receptor modulators | NOVARTIS AG (CH) | 2015-06-09 | — | — | US | disclosed |
| US-20140329876-A1 | PYRAZOLINE DERIVATIVES AND THEIR USE AS SELECTIVE ANDROGEN RECEPTOR MODULATORS | NOVARTIS AG (CH) | 2014-11-06 | — | — | US | disclosed |