Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENGASE | Q8NFI3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16217602 | 0.71 | — | — | |
| SCHEMBL17972860 | 0.69 | POLB (0.33) | — | |
| SCHEMBL761653 | 0.62 | — | — | |
| SCHEMBL4368534 | 0.61 | MMP2 (0.50) | — | |
| SCHEMBL30476580 | 0.61 | MMP2 (0.50) | — | |
| SCHEMBL8303532 | 0.61 | SMN1; SMN2 (0.43) | ENGASE | |
| SCHEMBL8303525 | 0.61 | SMN1; SMN2 (0.43) | ENGASE | |
| SCHEMBL89463 | 0.61 | ALDH1A1 (0.37) | — | |
| SCHEMBL22834149 | 0.61 | — | — | |
| SCHEMBL14381065 | 0.60 | BRD4 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1852712-B | Dual NK1/NK3 antagonists for treating schizophrenia | HOFFMANN LA ROCHE | 2010-06-09 | — | — | CN | disclosed |
| CN-1852712-A | Dual NK1/NK3 antagonists for treating schizophrenia | HOFFMANN LA ROCHE (CH) | 2006-10-25 | — | — | CN | disclosed |