Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 9/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | APEX1 | P27695 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17235958 | 0.96 | RECQL (0.56) | RECQLGAAFAAHMEN1KMT2A | |
| SCHEMBL17002032 | 0.88 | FAAH (0.64) | GAAFAAHMEN1KMT2ADNM1 | |
| SCHEMBL16217796 | 0.88 | RECQL (0.48) | RECQLGAAFAAHMEN1KMT2A | |
| SCHEMBL16217882 | 0.88 | RECQL (0.48) | RECQLGAAFAAHMEN1KMT2A | |
| SCHEMBL16217797 | 0.88 | RECQL (0.48) | RECQLGAAFAAHMEN1KMT2A | |
| SCHEMBL17235914 | 0.86 | TDP1 (0.41) | RECQLGAAFAAHMEN1KMT2A | |
| SCHEMBL16221906 | 0.86 | RECQL (0.47) | RECQLGAAFAAHMEN1KMT2A | |
| SCHEMBL20053455 | 0.84 | RECQL (0.46) | RECQLGAAFAAHMEN1KMT2A | |
| SCHEMBL19477899 | 0.84 | FAAH (0.60) | RECQLGAAFAAHMEN1KMT2A | |
| SCHEMBL20643453 | 0.83 | RECQL (0.44) | RECQLGAAFAAHMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014179629-A2 | COMPOSITIONS AND METHODS | ISIS PHARMACEUTICALS, INC. (US) | 2014-11-06 | — | — | WO | disclosed |
| WO-2014179620-A1 | CONJUGATED ANTISENSE COMPOUNDS AND THEIR USE | ISIS PHARMACEUTICALS, INC. (US) | 2014-11-06 | — | — | WO | disclosed |