SCHEMBL162184

SCHEMBL162184

COc1cccnc1Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30454545 1.00
Hydrochloric Acid SCHEMBL28030641 0.98 PLAU (0.46)
Ammonia Solution, Strong SCHEMBL28240370 0.98 PLAU (0.46)
Cyanide SCHEMBL28298857 0.94 PLAU (0.43)
Formaldehyde SCHEMBL28298897 0.94 PLAU (0.43)
Pyridine SCHEMBL5263081 0.90 PLAU (0.41)
Formic Acid SCHEMBL28244691 0.89 TRIM24 (0.47)
Formic Acid Methyl Ester SCHEMBL27958597 0.89 TRIM24 (0.47)
Formic Acid Methyl Ester SCHEMBL28061228 0.82 TRIM24 (0.41)
SCHEMBL30320727 0.79 S1PR4 (0.47)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 777 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110015987-B Preparation method of 2,3 '-dimethoxy- [2,4' ] bipyridyl 南京合巨药业有限公司 2020-11-20 CN claimed
CN-110713456-A Preparation method of 2-bromo-3-methoxypyridine 常州传侑环保科技有限公司 2020-01-21 CN claimed
CN-109748862-A A kind of preparation method of the bromo- 3-Methoxy Pyridine of 2- 丹阳市宁大卫防检测技术有限公司 2019-05-14 CN claimed
CN-106164047-A 1,2 substituted cyclopentanes as orexin receptor antagonists 武田药品工业株式会社 2016-11-23 CN claimed
CN-105209031-A Novel antiviral agents against HBV infection UNIV DREXEL 2015-12-30 CN claimed
CN-105017136-A 2-bromo-3-methoxypyridine preparation method CHEN JIMEI 2015-11-04 CN claimed
CN-103483247-B Preparation method of 2-bromo-3-methoxypyridine BEIJING GREENCHEM TECHNOLOGY CO LTD 2015-05-13 CN claimed
CN-103483247-A Preparation method of 2-bromo-3-methoxypyridine BEIJING GREENCHEM TECHNOLOGY CO LTD 2014-01-01 CN claimed
US-20260001845-A1 MITOGEN-ACTIVATED PROTEIN KINASE (MEK) INHIBITORS NESTED THERAPEUTICS INC (US) 2026-01-01 US disclosed
EP-4661966-A1 COMPOUNDS, COMPOSITIONS, AND METHODS OF USE THEREOF Type6 Therapeutics, Inc. (US) 2025-12-17 EP disclosed
EP-4655304-A1 MACROCYCLIC AMINOPYRIDINE COMPOUNDS AS EGFR INHIBITORS Yuhan Corporation (KR) 2025-12-03 EP disclosed
EP-4642782-A2 ALPHA-V-BETA-8 INTEGRIN INHIBITORS AND USES THEREOF Pliant Therapeutics, Inc. (US) 2025-11-05 EP disclosed
US-12454547-B2 Steroidal compositions and methods of treating lipogenic cancers Asteroid Therapeutics (US) 2025-10-28 US disclosed
US-20250325552-A1 SUBSTITUTED THIADIAZOLYL DERIVATIVES AS DNA POLYMERASE THETA INHIBITORS IDEAYA BIOSCIENCES INC (US) 2025-10-23 US disclosed
US-4937251-A TREATING ASTHMA AND BRONCHITIS; ADRENERGIC STIMULANTS GLAXO GROUP LIMITED (GB) 1990-06-26 US disclosed
EP-0181163-B1 HETEROCYCLIC PHENOXY DERIVATIVES HAVING AN ANTIHISTAMINE H2 ACTIVITY SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1989-12-20 EP disclosed
EP-0345808-A1 1-Indolylalkyl-4-(substituted-pyridinyl)piperazines Bristol-Myers Squibb Company (US) 1989-12-13 EP disclosed
US-4681883-A Histamine H2 -antagonist oxazole and thiazole derivatives and compositions therefor SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1987-07-21 US disclosed
CN-85108132-A Compounds process for production thereof 1986-07-16 CN disclosed
EP-0181163-A2 Heterocyclic phenoxy derivatives having an antihistamine H2 activity SMITH KLINE & FRENCH LABORATORIES LIMITED (GB) 1986-05-14 EP disclosed