⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL162184 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL28030641 | 0.98 | PLAU (0.46) | — | |
| Ammonia Solution, Strong SCHEMBL28240370 | 0.98 | PLAU (0.46) | — | |
| Cyanide SCHEMBL28298857 | 0.94 | PLAU (0.43) | — | |
| Formaldehyde SCHEMBL28298897 | 0.94 | PLAU (0.43) | — | |
| Pyridine SCHEMBL5263081 | 0.90 | PLAU (0.41) | — | |
| Formic Acid SCHEMBL28244691 | 0.89 | TRIM24 (0.47) | — | |
| Formic Acid Methyl Ester SCHEMBL27958597 | 0.89 | TRIM24 (0.47) | — | |
| Formic Acid Methyl Ester SCHEMBL28061228 | 0.82 | TRIM24 (0.41) | — | |
| SCHEMBL30320727 | 0.79 | S1PR4 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4551558-A2 | MITOGEN-ACTIVATED PROTEIN KINASE (MEK) INHIBITORS | Nested Therapeutics, Inc. (US) | 2025-05-14 | — | — | EP | disclosed |
| WO-2025072539-A1 | AMINO ACID COMPOUNDS WITH NITROGEN LINKERS AND USES THEREOF | PLIANT THERAPEUTICS, INC. (US) | 2025-04-03 | — | — | WO | disclosed |
| WO-2024010925-A2 | MITOGEN-ACTIVATED PROTEIN KINASE (MEK) INHIBITORS | NESTED THERAPEUTICS, INC. (US) | 2024-01-11 | — | — | WO | disclosed |
| WO-2023122000-A1 | BCL-2 INHIBITORS | NEWAVE PHARMACEUTICAL INC. (US) | 2023-06-29 | — | — | WO | disclosed |
| WO-2023121713-A1 | BCL-2 INHIBITORS | NEW AVE PHARMACEUTICAL INC. (US) | 2023-06-29 | — | — | WO | disclosed |