⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26944775 | 0.80 | ALDH1A1 (0.32) | — | |
| SCHEMBL18567596 | 0.79 | ALDH1A1 (0.34) | — | |
| SCHEMBL15833834 | 0.79 | ALDH1A1 (0.34) | — | |
| SCHEMBL13862874 | 0.79 | ALDH1A1 (0.34) | — | |
| SCHEMBL24667598 | 0.76 | — | — | |
| SCHEMBL26944836 | 0.76 | ALDH1A1 (0.30) | — | |
| SCHEMBL15557458 | 0.75 | — | — | |
| SCHEMBL16937877 | 0.74 | — | — | |
| SCHEMBL30736104 | 0.71 | — | — | |
| SCHEMBL4763204 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11744831-B2 | Antiviral JAK inhibitors useful in treating or preventing retroviral and other viral infections | EMORY UNIVERSITY (US) | 2023-09-05 | — | — | US | disclosed |
| US-20170312283-A1 | ANTIVIRAL JAK INHIBITORS USEFUL IN TREATING OR PREVENTING RETROVIRAL AND OTHER VIRAL INFECTIONS | THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS AFFAIRS | 2017-11-02 | — | — | US | disclosed |
| US-9662332-B2 | Antiviral JAK inhibitors useful in treating or preventing retroviral and other viral infections | EMORY UNIVERSITY (US) | 2017-05-30 | — | — | US | disclosed |
| US-20140328793-A1 | ANTIVIRAL JAK INHIBITORS USEFUL IN TREATING OR PREVENTING RETROVIRAL AND OTHER VIRAL INFECTIONS | EMORY UNIVERSITY (US) | 2014-11-06 | — | — | US | disclosed |