Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K12 | Q12852 | 19/20 | 0.63 |
| ▸ | DLK1 | P80370 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16220349 | 0.80 | MAP3K12 (0.90) | MAP3K12 | |
| SCHEMBL16220217 | 0.79 | MAP3K12 (0.77) | MAP3K12DLK1 | |
| SCHEMBL16220346 | 0.78 | MAP3K12 (1.00) | MAP3K12DLK1 | |
| SCHEMBL16220347 | 0.77 | MAP3K12 (0.91) | MAP3K12DLK1SYK | |
| SCHEMBL22239459 | 0.76 | MAP3K12 (0.74) | MAP3K12DLK1SYK | |
| SCHEMBL16220402 | 0.75 | MAP3K12 (0.58) | MAP3K12 | |
| SCHEMBL16220040 | 0.73 | MAP3K12 (1.00) | MAP3K12 | |
| SCHEMBL19771657 | 0.72 | MAP3K12 (0.73) | MAP3K12DLK1SYK | |
| SCHEMBL16220029 | 0.70 | MAP3K12 (0.79) | MAP3K12 | |
| SCHEMBL16220058 | 0.68 | MAP3K12 (0.75) | MAP3K12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014177524-A1 | C-LINKED HETEROCYCLOALKYL SUBSTITUTED PYRIMIDINES AND THEIR USES | F. HOFFMANN-LA ROCHE AG (CH) | 2014-11-06 | — | — | WO | disclosed |