Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.39 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5223609 | 0.87 | USP2 (0.41) | USP2SMN1; SMN2ESR2NR1H2MAPT | |
| SCHEMBL2123557 | 0.87 | USP2 (0.41) | USP2SMN1; SMN2ESR2NR1H2MAPT | |
| SCHEMBL16221362 | 0.85 | USP2 (0.41) | USP2SMN1; SMN2ESR2NR1H2MAPT | |
| SCHEMBL17868613 | 0.85 | DDB1 (0.41) | USP2SMN1; SMN2ESR2NR1H2MAPT | |
| SCHEMBL173439 | 0.84 | PDE4B (0.41) | USP2SMN1; SMN2ESR2NR1H2MAPT | |
| SCHEMBL18815293 | 0.83 | MAPT (0.42) | USP2SMN1; SMN2ESR2NR1H2MAPT | |
| SCHEMBL18359468 | 0.83 | PDK4 (0.40) | USP2SMN1; SMN2ESR2NR1H2MAPT | |
| SCHEMBL1007010 | 0.83 | DDB1 (0.40) | USP2SMN1; SMN2ESR2NR1H2MAPT | |
| SCHEMBL14251617 | 0.83 | HPGD (0.43) | USP2SMN1; SMN2ESR2NR1H2MAPT | |
| SCHEMBL17868696 | 0.82 | ESR2 (0.39) | USP2SMN1; SMN2ESR2NR1H2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8933224-B2 | Triazine derivatives | PFIZER INC. (US) | 2015-01-13 | — | — | US | disclosed |
| US-20140329820-A1 | Triazine Derivatives | PFIZER INC. (US) | 2014-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140329820-A1 | Triazine Derivatives | PDE12, PDE5A, PDE10A | USP2 1531/4885SMN1; SMN2 4124/4885ESR2 2152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.