Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.40 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.40 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.39 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.39 |
| ▸ | F2R | P25116 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2123557 | 0.88 | USP2 (0.41) | USP2SMN1; SMN2GPR119ESR2ADORA1 | |
| SCHEMBL17868613 | 0.87 | DDB1 (0.41) | USP2SMN1; SMN2GPR119ESR2ADORA1 | |
| SCHEMBL16221362 | 0.87 | USP2 (0.41) | USP2SMN1; SMN2GPR119ESR2ADORA1 | |
| SCHEMBL28974047 | 0.87 | GPR119 (0.49) | USP2SMN1; SMN2GPR119MAPTKDM4E | |
| SCHEMBL16220613 | 0.87 | USP2 (0.41) | USP2SMN1; SMN2GPR119ESR2ADORA1 | |
| SCHEMBL173439 | 0.85 | PDE4B (0.41) | USP2SMN1; SMN2ESR2ADORA1NR1H2 | |
| SCHEMBL24812373 | 0.84 | NR1H2 (0.42) | USP2SMN1; SMN2GPR119ESR2ADORA1 | |
| SCHEMBL18084745 | 0.84 | HPGD (0.49) | USP2SMN1; SMN2GPR119MAPTKDM4E | |
| SCHEMBL1007010 | 0.84 | DDB1 (0.40) | USP2SMN1; SMN2GPR119ESR2NR1H2 | |
| SCHEMBL18815293 | 0.84 | MAPT (0.42) | USP2SMN1; SMN2GPR119ESR2ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119997956-A | Pharmaceutical composition and use thereof for treating glioma | 奇默里克斯公司 | 2025-05-13 | — | — | CN | disclosed |
| CN-111032039-B | Compounds for the prevention and treatment of medical disorders and uses thereof | 卡莱克汀科学有限责任公司 | 2024-03-26 | — | — | CN | disclosed |
| CN-116173036-A | E Mi Litong for glioma | 昂克希尔迪克斯有限公司 | 2023-05-30 | — | — | CN | disclosed |
| CN-110563717-B | Piperidine CXCR7 receptor modulators | 爱杜西亚药品有限公司 | 2022-08-09 | — | — | CN | disclosed |
| CN-111818919-A | Imipritone for glioma | 昂克希尔迪克斯有限公司 | 2020-10-23 | — | — | CN | disclosed |
| CN-109311980-A | G protein-coupled receptor (GPCR) modulation by emilienone (IMIPRIDONES) | 昂克希尔迪克斯有限公司 | 2019-02-05 | — | — | CN | disclosed |
| EP-3408298-A2 | G PROTEIN-COUPLED RECEPTOR (GPCR) MODULATION BY IMIPRIDONES | Oncoceutics, Inc. (US) | 2018-12-05 | — | — | EP | disclosed |
| WO-2017132661-A2 | G PROTEIN-COUPLED RECEPTOR (GPCR) MODULATION BY IMIPRIDONES | ONCOCEUTICS, INC. (US) | 2017-08-03 | — | — | WO | disclosed |
| EP-3068401-A1 | 7-BENZYL-4-(2-METHYLBENZYL)-2,4,6,7,8,9-HEXAHYDROIMIDAZO[1,2-A]PYRIDO[3,4-E]PYRIMIDIN-5(1H)-ONE, SALTS THEREOF AND METHODS OF USE | Oncoceutics, Inc. (US) | 2016-09-21 | — | — | EP | disclosed |
| WO-2015073109-A1 | 7-BENZYL-4-(2-METHYLBENZYL)-2,4,6,7,8,9-HEXAHYDROIMIDAZO[1,2-A]PYRIDO[3,4-E]PYRIMIDIN-5(1H)-ONE, SALTS THEREOF AND METHODS OF USE | ONCOCEUTICS, INC. (US) | 2015-05-21 | — | — | WO | disclosed |
| US-6867202-B1 | Increasing level of endogenous growth hormone using growth hormone secretagogue such as 2-amino-N-(2-(3a-benzyl-2-methy-3-oxo-2,3,3a,4,6,7-hexahydro-pyrazolo-(4,3 -c)pyridin-5-yl)-1-benzyloxymethyl-2-oxo-ethyl)-isobutyramide tartarate salt | PFIZER INC. (US) | 2005-03-15 | — | — | US | disclosed |
| EP-1204660-B1 | SEROTONERGIC BENZOTHIOPHENES | LILLY CO ELI (US) | 2004-10-20 | — | — | EP | disclosed |
| EP-1370550-A1 | QUINOLYL PROPYL PIPERIDINE DERIVATIVES, THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING SAME | Aventis Pharma S.A. (FR) | 2003-12-17 | — | — | EP | disclosed |
| EP-1204659-B1 | SEROTONERGIC BENZOFURANS | LILLY CO ELI (US) | 2003-11-26 | — | — | EP | disclosed |
| WO-2002072572-A1 | QUINOLYL PROPYL PIPERIDINE DERIVATIVES, THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING SAME | AVENTIS PHARMA S.A. (FR) | 2002-09-19 | — | — | WO | disclosed |
| EP-1240168-A1 | BICYCLIC INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 | CHIRON CORPORATION (US) | 2002-09-18 | — | — | EP | disclosed |
| WO-2001044246-A1 | BICYCLIC INHIBITORS OF GLYCOGEN SYNTHASE KINASE 3 | CHIRON CORPORATION (US) | 2001-06-21 | — | — | WO | disclosed |
| JP-2000143610-A | N-TERTIARY-BUTOXYCARBONYL-3,3'-IMINODIPROPIONATE, ITS PRODUCTION, AND PRODUCTION OF 1-TERTIARY- BUTOXYCARBONYL-4-OXO-3-PIPERIDINECARBOXYLATE | KOEI CHEM CO LTD | 2000-05-26 | — | — | JP | disclosed |
| EP-0805681-A4 | TOCOLYTIC OXYTOCIN RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 1998-05-06 | — | — | EP | disclosed |
| EP-0805681-A1 | TOCOLYTIC OXYTOCIN RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 1997-11-12 | — | — | EP | disclosed |