Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.39 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.37 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16217172 | 0.85 | ESR2 (0.43) | ESR2NR1H2USP2SMN1; SMN2ADORA1 | |
| SCHEMBL10655954 | 0.85 | ESR2 (0.46) | ESR2NR1H2USP2SMN1; SMN2ADORA1 | |
| SCHEMBL16380131 | 0.84 | ESR2 (0.42) | ESR2NR1H2USP2SMN1; SMN2ADORA1 | |
| SCHEMBL22481977 | 0.83 | USP2 (0.42) | ESR2NR1H2USP2SMN1; SMN2ADORA1 | |
| SCHEMBL2576275 | 0.83 | ADORA1 (0.46) | ESR2NR1H2USP2SMN1; SMN2ADORA1 | |
| SCHEMBL20424276 | 0.82 | HDAC4 (0.41) | ESR2NR1H2USP2SMN1; SMN2ADORA1 | |
| SCHEMBL22621730 | 0.80 | HSP90AA1 (0.43) | ESR2NR1H2USP2SMN1; SMN2ADORA1 | |
| SCHEMBL16220618 | 0.80 | MAPT (0.43) | ESR2NR1H2USP2SMN1; SMN2ADORA1 | |
| SCHEMBL3441391 | 0.79 | KMT2A (0.57) | USP2SMN1; SMN2ALDH1A1POLBMAPT | |
| SCHEMBL2582147 | 0.78 | HSP90AA1 (0.58) | ESR2NR1H2USP2SMN1; SMN2ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140329820-A1 | Triazine Derivatives | PFIZER INC. (US) | 2014-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140329820-A1 | Triazine Derivatives | PDE12, PDE5A, PDE10A | ESR2 2152/4885NR1H2 869/4885USP2 1531/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.