Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 6/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2576275 | 0.90 | ADORA1 (0.46) | USP2ALDH1A1POLBESR2ADORA1 | |
| SCHEMBL22621730 | 0.86 | HSP90AA1 (0.43) | USP2ALDH1A1POLBESR2ADORA1 | |
| SCHEMBL3441391 | 0.85 | KMT2A (0.57) | USP2ALDH1A1POLBHSP90AA1SMN1; SMN2 | |
| SCHEMBL2582147 | 0.84 | HSP90AA1 (0.58) | USP2ALDH1A1POLBESR2ADORA1 | |
| SCHEMBL16217172 | 0.84 | ESR2 (0.43) | USP2ALDH1A1POLBESR2ADORA1 | |
| SCHEMBL10655954 | 0.84 | ESR2 (0.46) | USP2ALDH1A1POLBESR2ADORA1 | |
| SCHEMBL16220615 | 0.83 | ESR2 (0.45) | USP2ALDH1A1POLBESR2ADORA1 | |
| SCHEMBL16380131 | 0.83 | ESR2 (0.42) | USP2ALDH1A1POLBESR2ADORA1 | |
| SCHEMBL22615316 | 0.83 | SMN1; SMN2 (0.55) | USP2ALDH1A1POLBHSP90AA1SMN1; SMN2 | |
| SCHEMBL2587066 | 0.82 | USP2 (0.41) | USP2ALDH1A1POLBHSP90AA1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020198583-A1 | BICYCLIC JAK INHIBITORS AND USES THEREOF | INSILICO MEDICINE IP LIMITED (CN) | 2020-10-01 | — | — | WO | disclosed |