Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 15/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 8/20 | 0.38 |
| ▸ | BACE1 | P56817 | 5/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1622105 | 1.00 | ADRB3 (0.44) | ADRB3ADRB1BACE1 | |
| SCHEMBL5178403 | 0.93 | ADRB3 (0.46) | ADRB3ADRB1BACE1 | |
| SCHEMBL1620342 | 0.85 | ADRB3 (0.44) | ADRB3ADRB1 | |
| SCHEMBL1620339 | 0.85 | ADRB3 (0.44) | ADRB3ADRB1 | |
| SCHEMBL1622109 | 0.85 | ADRB3 (0.49) | ADRB3ADRB1 | |
| SCHEMBL1622111 | 0.85 | ADRB3 (0.49) | ADRB3ADRB1 | |
| SCHEMBL1628497 | 0.84 | ADRB3 (0.53) | ADRB3ADRB1 | |
| SCHEMBL1622355 | 0.84 | ADRB3 (0.54) | ADRB3ADRB1 | |
| SCHEMBL5703886 | 0.80 | ADRB3 (0.66) | ADRB3ADRB1 | |
| SCHEMBL1622455 | 0.78 | ADRB3 (0.46) | ADRB3ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7928264-B2 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2011-04-19 | — | — | US | disclosed |
| US-20080039506-A1 | Aminoalcohol Derivatives | ASTELLAS PHARMA INC. (JP) | 2008-02-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080039506-A1 | Aminoalcohol Derivatives | HRH4, HRH2, CBR3 | ADRB3 40/4885ADRB1 19/4885BACE1 3227/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.