Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 17/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 8/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1622105 | 0.93 | ADRB3 (0.44) | ADRB3ADRB1BACE1 | |
| SCHEMBL1622101 | 0.93 | ADRB3 (0.44) | ADRB3ADRB1BACE1 | |
| SCHEMBL1622111 | 0.92 | ADRB3 (0.49) | ADRB3ADRB1MEN1KMT2A | |
| SCHEMBL1622109 | 0.92 | ADRB3 (0.49) | ADRB3ADRB1MEN1KMT2A | |
| SCHEMBL1628497 | 0.91 | ADRB3 (0.53) | ADRB3ADRB1 | |
| SCHEMBL1622355 | 0.85 | ADRB3 (0.54) | ADRB3ADRB1 | |
| SCHEMBL1622455 | 0.85 | ADRB3 (0.46) | ADRB3ADRB1 | |
| SCHEMBL1622368 | 0.84 | ADRB3 (0.47) | ADRB3ADRB1 | |
| SCHEMBL5178405 | 0.83 | ADRB3 (0.47) | ADRB3ADRB1 | |
| SCHEMBL5241577 | 0.83 | ADRB3 (0.49) | ADRB3ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1791811-A1 | AMINOALCOHOL DERIVATIVES | Astellas Pharma Inc. (JP) | 2007-06-06 | — | — | EP | disclosed |
| WO-2006033446-A1 | AMINOALCOHOL DERIVATIVES | ASTELLAS PHARMA INC. (JP) | 2006-03-30 | — | — | WO | disclosed |