Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 20/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15168382 | 0.86 | SYK (0.62) | SYK | |
| SCHEMBL16223732 | 0.83 | SYK (0.65) | SYK | |
| SCHEMBL16223741 | 0.82 | SYK (0.65) | SYK | |
| SCHEMBL2423668 | 0.77 | SYK (1.00) | SYK | |
| SCHEMBL18714101 | 0.77 | SYK (0.80) | SYK | |
| SCHEMBL16223740 | 0.77 | SYK (0.73) | SYK | |
| SCHEMBL2425074 | 0.77 | SYK (0.65) | SYK | |
| SCHEMBL18454407 | 0.76 | SYK (0.67) | SYK | |
| SCHEMBL6911190 | 0.74 | SYK (0.78) | SYK | |
| SCHEMBL2427923 | 0.74 | SYK (0.63) | SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2545052-B1 | IMIDAZOPYRIDINES SYK INHIBITORS | GILEAD CONNECTICUT INC (US) | 2014-11-12 | — | — | EP | disclosed |