Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 20/20 | 0.67 |
| ▸ | CD63 | P08962 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18714101 | 0.83 | SYK (0.80) | SYK | |
| SCHEMBL2423668 | 0.80 | SYK (1.00) | SYK | |
| SCHEMBL6911219 | 0.78 | SYK (1.00) | SYK | |
| SCHEMBL2425074 | 0.78 | SYK (0.65) | SYK | |
| SCHEMBL6911190 | 0.77 | SYK (0.78) | SYK | |
| SCHEMBL2427923 | 0.77 | SYK (0.63) | SYK | |
| SCHEMBL15182404 | 0.77 | SYK (0.61) | SYK | |
| SCHEMBL16223559 | 0.76 | SYK (0.62) | SYK | |
| SCHEMBL15168382 | 0.76 | SYK (0.62) | SYK | |
| SCHEMBL2425263 | 0.71 | SYK (0.84) | SYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3123864-A1 | IMIDAZOPYRAZINE SYK INHIBITORS | Gilead Connecticut, Inc. (US) | 2017-02-01 | — | — | EP | disclosed |