Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 5/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.36 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA3 | P07451 | 2/20 | 0.35 |
| ▸ | CA4 | P22748 | 2/20 | 0.35 |
| ▸ | CA6 | P23280 | 2/20 | 0.35 |
| ▸ | CA5A | P35218 | 2/20 | 0.35 |
| ▸ | CA7 | P43166 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.35 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | FLT1 | P17948 | 3/20 | 0.34 |
| ▸ | FLT4 | P35916 | 3/20 | 0.34 |
| ▸ | KDR | P35968 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1620530 | 0.85 | ADRB3 (0.35) | ADRB3ADRB1CA2CA12CA1 | |
| SCHEMBL1622188 | 0.83 | ALDH1A1 (0.38) | ALDH1A1ADRB3ADRB1CA2CA12 | |
| SCHEMBL4583570 | 0.79 | ADRB3 (0.51) | ADRB3ADRB1MAPTFLT1FLT4 | |
| SCHEMBL1622237 | 0.74 | SCN9A (0.40) | ADRB3ADRB1 | |
| SCHEMBL4468280 | 0.73 | NR4A2 (0.46) | ALDH1A1CA2CA12CA1CA7 | |
| SCHEMBL1620614 | 0.71 | ADRB3 (0.37) | ADRB3ADRB1FLT1FLT4KDR | |
| SCHEMBL1622644 | 0.70 | BCL2L1 (0.36) | ADRB3ADRB1CA2CA12CA1 | |
| SCHEMBL4167084 | 0.68 | MAPT (0.47) | ALDH1A1ADRB3ADRB1TDP1MAPT | |
| SCHEMBL27647574 | 0.68 | MAPT (0.43) | ALDH1A1MAPTHPGDKDM4ENPSR1 | |
| SCHEMBL4584858 | 0.67 | ADRB3 (0.41) | ADRB3ADRB1FLT1FLT4KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7928264-B2 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2011-04-19 | — | — | US | disclosed |
| US-20080039506-A1 | Aminoalcohol Derivatives | ASTELLAS PHARMA INC. (JP) | 2008-02-14 | — | — | US | disclosed |
| EP-1791811-A1 | AMINOALCOHOL DERIVATIVES | Astellas Pharma Inc. (JP) | 2007-06-06 | — | — | EP | disclosed |
| WO-2006033446-A1 | AMINOALCOHOL DERIVATIVES | ASTELLAS PHARMA INC. (JP) | 2006-03-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080039506-A1 | Aminoalcohol Derivatives | HRH4, HRH2, CBR3 | ALDH1A1 363/4885ADRB3 40/4885ADRB1 19/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.