Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 4/20 | 0.59 |
| ▸ | PPARD | Q03181 | 3/20 | 0.59 |
| ▸ | PPARA | Q07869 | 3/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.53 |
| ▸ | TRPM7 | Q96QT4 | 1/20 | 0.53 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.53 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.52 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.44 |
| ▸ | EPAS1 | Q99814 | 4/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | PTGES | O14684 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | BACE1 | P56817 | 1/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16224903 | 0.85 | PPARG (0.67) | PPARGPPARDPPARASLC6A3TRPM7 | |
| SCHEMBL11759762 | 0.83 | CYP19A1 (0.67) | PPARGPPARDPPARASLC6A3TRPM7 | |
| SCHEMBL6434707 | 0.78 | KAT8 (0.49) | PPARGPPARDPPARA | |
| SCHEMBL2109843 | 0.75 | PPARG (1.00) | PPARGPPARDPPARASLC6A3TRPM7 | |
| SCHEMBL23121448 | 0.73 | KAT8 (0.47) | PPARGPPARA | |
| SCHEMBL5588198 | 0.73 | KAT8 (0.47) | PPARGPPARA | |
| SCHEMBL5589035 | 0.73 | KAT8 (0.47) | PPARGPPARA | |
| SCHEMBL5588294 | 0.73 | KAT8 (0.47) | PPARGPPARA | |
| Ammonia Solution, Strong SCHEMBL26679451 | 0.73 | FFAR1 (0.49) | PPARGPPARDPPARAPTPN1 | |
| SCHEMBL15361077 | 0.72 | MAOB (0.49) | PPARGPPARDPPARAHIF1AEPAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014177593-A1 | AMORFRUTIN ANALOGS AS PPARGAMMA-MODULATORS | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2014-11-06 | — | — | WO | disclosed |