Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 3/20 | 0.67 |
| ▸ | PPARD | Q03181 | 3/20 | 0.67 |
| ▸ | PPARA | Q07869 | 3/20 | 0.67 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | TRPM7 | Q96QT4 | 1/20 | 0.48 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.48 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.47 |
| ▸ | PTGES | O14684 | 2/20 | 0.46 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.46 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | BACE1 | P56817 | 1/20 | 0.46 |
| ▸ | CRHBP | P24387 | 1/20 | 0.45 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.45 |
| ▸ | IMPDH2 | P12268 | 3/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.40 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16224901 | 0.85 | PPARG (0.59) | PPARGPPARDPPARASLC6A3TRPM7 | |
| SCHEMBL16212213 | 0.81 | PPARG (1.00) | PPARGPPARDPPARAPTGESALOX5 | |
| SCHEMBL2109843 | 0.77 | PPARG (1.00) | PPARGPPARDPPARASLC6A3TRPM7 | |
| SCHEMBL5587316 | 0.76 | PPARA (0.47) | PPARGPPARDPPARAPTGESALOX5 | |
| SCHEMBL5589023 | 0.74 | ALOX5 (0.48) | PPARGPPARDPPARAPTGESALOX5 | |
| SCHEMBL5586683 | 0.74 | ALOX5 (0.48) | PPARGPPARDPPARAPTGESALOX5 | |
| SCHEMBL5587087 | 0.74 | ALOX5 (0.48) | PPARGPPARDPPARAPTGESALOX5 | |
| SCHEMBL5588254 | 0.74 | ALOX5 (0.48) | PPARGPPARDPPARAPTGESALOX5 | |
| SCHEMBL5588437 | 0.74 | ALOX5 (0.48) | PPARGPPARDPPARAPTGESALOX5 | |
| SCHEMBL16212954 | 0.74 | PPARG (0.78) | PPARGPPARDPPARAPTGESALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014177593-A1 | AMORFRUTIN ANALOGS AS PPARGAMMA-MODULATORS | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2014-11-06 | — | — | WO | disclosed |