SCHEMBL1622513

SCHEMBL1622513

CCCCCCCCCCCCCCCCCC(=O)N[C@@H](C=O)[C@@H](O)[C@H](O)[C@H](O)CO

nearest known ligand 0.59

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.54
KMT2A Q03164 3/20 0.54
DEGS1 O15121 3/20 0.50
FAAH O00519 2/20 0.49
MAPK1 P28482 1/20 0.49
CETP P11597 3/20 0.48
THRB P10828 1/20 0.48
ASAH1 Q13510 1/20 0.45
DNM1 Q05193 1/20 0.44
ASAH2 Q9NR71 1/20 0.44
PLA2G4A P47712 2/20 0.43
CERT1 Q9Y5P4 2/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1623032 1.00 MEN1 (0.54) MEN1KMT2ADEGS1FAAHMAPK1
SCHEMBL9709528 1.00 MEN1 (0.54) MEN1KMT2ADEGS1FAAHMAPK1
SCHEMBL1623366 1.00 MEN1 (0.54) MEN1KMT2ADEGS1FAAHMAPK1
SCHEMBL679503 1.00 MEN1 (0.54) MEN1KMT2ADEGS1FAAHMAPK1
SCHEMBL1623037 1.00 MEN1 (0.54) MEN1KMT2ADEGS1FAAHMAPK1
SCHEMBL10958796 1.00 MEN1 (0.54) MEN1KMT2ADEGS1FAAHMAPK1
SCHEMBL5821483 1.00 MEN1 (0.54) MEN1KMT2ADEGS1FAAHMAPK1
SCHEMBL5185943 1.00 MEN1 (0.54) MEN1KMT2ADEGS1FAAHMAPK1
SCHEMBL557791 0.99 MEN1 (0.51) MEN1KMT2ADEGS1FAAHMAPK1
SCHEMBL5326495 0.99 MEN1 (0.51) MEN1KMT2ADEGS1FAAHMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4323561-A Process of enhancing immmunogenic response in mammals by the administration of synthetic glycolipid adjuvants TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 1982-04-06 US claimed
US-7928090-B2 External preparation composition LION CORPORATION (JP) 2011-04-19 US disclosed
US-7763595-B2 Method of treatment of skin with external preparation composition LION CORPORATION (JP) 2010-07-27 US disclosed
US-20100074856-A1 EXTERNAL PREPARATION COMPOSITION LION CORPORATION (JP) 2010-03-25 US disclosed
US-20090048211-A1 EXTERNAL PREPARATION COMPOSITION LION CORPORATION (JP) 2009-02-19 US disclosed
EP-1941863-A2 External preparation composition Lion Corporation (JP) 2008-07-09 EP disclosed
EP-1917956-A2 External preparation composition Lion Corporation (JP) 2008-05-07 EP disclosed
JP-2006008565-A MICROCAPSULE INCLUDING GLUCOSAMINE FATTY ACID AMIDE COMPOUND AND COMPOSITION CONTAINING THE SAME LION CORP 2006-01-12 JP disclosed
US-20050239749-A1 External preparation LION CORPORATION (JP) 2005-10-27 US disclosed
EP-1543821-A1 EXTERNAL PREPARATION Lion Corporation (JP) 2005-06-22 EP disclosed
EP-0575517-A1 LIPID A ANALOG/IMMUNOGENIC CARRIER CONJUGATES, THE USE THEREOF AS VACCINES AND POLYVALENT HYPERIMMUNE GAMMAGLOBULINS UNIVAX BIOLOGICS INCORPORATED (US) 1993-12-29 EP disclosed
EP-0484403-A4 LIPID A ANALOG/IMMUNOGENIC CARRIER CONJUGATES AND THE USE THEREOF AS VACCINES 1993-03-17 EP disclosed
WO-1992016230-A1 LIPID A ANALOG/IMMUNOGENIC CARRIER CONJUGATES, THE USE THEREOF AS VACCINES AND POLYVALENT HYPERIMMUNE GAMMAGLOBULINS UNIVAX BIOLOGICS INCORPORATED (US) 1992-10-01 WO disclosed
EP-0484403-A1 LIPID A ANALOG/IMMUNOGENIC CARRIER CONJUGATES AND THE USE THEREOF AS VACCINES UNIVAX BIOLOGICS INCORPORATED (US) 1992-05-13 EP disclosed
WO-1991001750-A1 LIPID A ANALOG/IMMUNOGENIC CARRIER CONJUGATES AND THE USE THEREOF AS VACCINES UNIVAX BIOLOGICS, INC. (US) 1991-02-21 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050239749-A1 External preparation GLA, COLGALT1, GRN MEN1 4506/4885KMT2A 3492/4885DEGS1 62/4885
US-20100074856-A1 EXTERNAL PREPARATION COMPOSITION GLA, COLGALT1, DPM1 MEN1 4542/4885KMT2A 3763/4885DEGS1 30/4885
US-20090048211-A1 EXTERNAL PREPARATION COMPOSITION GLA, COLGALT1, DPM1 MEN1 4542/4885KMT2A 3763/4885DEGS1 30/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.