SCHEMBL557791

SCHEMBL557791

CCCCCC(=O)N[C@@H](C=O)[C@@H](O)[C@@H](O)[C@H](O)CO

nearest known ligand 0.60

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.51
KMT2A Q03164 3/20 0.51
DEGS1 O15121 3/20 0.48
FAAH O00519 2/20 0.46
MAPK1 P28482 1/20 0.46
CETP P11597 3/20 0.46
THRB P10828 2/20 0.46
ASAH1 Q13510 1/20 0.43
DNM1 Q05193 1/20 0.42
ASAH2 Q9NR71 1/20 0.42
KCNK3 O14649 1/20 0.42
ALDH1A1 P00352 1/20 0.42
CNR2 P34972 1/20 0.42
BLM P54132 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
PLA2G4A P47712 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5157353 1.00 MEN1 (0.51) MEN1KMT2ADEGS1FAAHMAPK1
SCHEMBL5326495 1.00 MEN1 (0.51) MEN1KMT2ADEGS1FAAHMAPK1
SCHEMBL1623032 0.99 MEN1 (0.54) MEN1KMT2ADEGS1FAAHMAPK1
SCHEMBL5821483 0.99 MEN1 (0.54) MEN1KMT2ADEGS1FAAHMAPK1
SCHEMBL10958796 0.99 MEN1 (0.54) MEN1KMT2ADEGS1FAAHMAPK1
SCHEMBL1623037 0.99 MEN1 (0.54) MEN1KMT2ADEGS1FAAHMAPK1
SCHEMBL1623366 0.99 MEN1 (0.54) MEN1KMT2ADEGS1FAAHMAPK1
SCHEMBL1622513 0.99 MEN1 (0.54) MEN1KMT2ADEGS1FAAHMAPK1
SCHEMBL5185943 0.99 MEN1 (0.54) MEN1KMT2ADEGS1FAAHMAPK1
SCHEMBL679503 0.99 MEN1 (0.54) MEN1KMT2ADEGS1FAAHMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120035320-A1 POLYACRIDINE NUCLEIC ACID DELIVERY PEPTIDE COMPLEXES UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) 2012-02-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120035320-A1 POLYACRIDINE NUCLEIC ACID DELIVERY PEPTIDE COMPLEXES NUP205, PABPC1, SARNP MEN1 1222/4885KMT2A 2891/4885DEGS1 4565/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.