Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 11/20 | 0.65 |
| ▸ | SLC10A2 | Q12908 | 2/20 | 0.65 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.65 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.65 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 4/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.62 |
| ▸ | USP2 | O75604 | 1/20 | 0.62 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | SHBG | P04278 | 1/20 | 0.52 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19705510 | 0.89 | GPBAR1 (0.74) | GPBAR1SLC10A2TBXA2RPDE3ANR1H4 | |
| SCHEMBL19705677 | 0.89 | GPBAR1 (0.74) | GPBAR1SLC10A2TBXA2RPDE3ANR1H4 | |
| SCHEMBL19705511 | 0.89 | GPBAR1 (0.74) | GPBAR1SLC10A2TBXA2RPDE3ANR1H4 | |
| SCHEMBL10884448 | 0.87 | GPBAR1 (0.73) | GPBAR1SLC10A2TBXA2RPDE3ANR1H4 | |
| SCHEMBL16227102 | 0.85 | GPBAR1 (0.70) | GPBAR1PDE3ANR1H4LMNAMEN1 | |
| SCHEMBL16226417 | 0.84 | GPBAR1 (0.77) | GPBAR1SLC10A2TBXA2RPDE3ANR1H4 | |
| SCHEMBL16227156 | 0.84 | GPBAR1 (0.77) | GPBAR1SLC10A2TBXA2RPDE3ANR1H4 | |
| SCHEMBL4279494 | 0.84 | GPBAR1 (0.68) | GPBAR1SLC10A2TBXA2RPDE3ANR1H4 | |
| SCHEMBL20008824 | 0.84 | MAPT (0.62) | GPBAR1SLC10A2TBXA2RPDE3ANR1H4 | |
| SCHEMBL4279489 | 0.84 | GPBAR1 (0.68) | GPBAR1SLC10A2TBXA2RPDE3ANR1H4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140335050-A1 | METHODS, COMPOSITIONS, AND KITS FOR THE TREATMENT OF CANCER | THE GENERAL HOSPITAL CORPORATION (US) | 2014-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140335050-A1 | METHODS, COMPOSITIONS, AND KITS FOR THE TREATMENT OF CANCER | IL2RA, CD74, IL2 | GPBAR1 77/4885SLC10A2 3818/4885TBXA2R 60/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.