Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 8/20 | 0.68 |
| ▸ | NR1H4 | Q96RI1 | 4/20 | 0.68 |
| ▸ | SLC10A2 | Q12908 | 2/20 | 0.68 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.68 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.60 |
| ▸ | USP2 | O75604 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | CASP7 | P55210 | 3/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | BLM | P54132 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.54 |
| ▸ | MDM4 | O15151 | 1/20 | 0.54 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.54 |
| ▸ | VDR | P11473 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4279494 | 1.00 | GPBAR1 (0.68) | GPBAR1NR1H4SLC10A2PDE3ATBXA2R | |
| SCHEMBL2293894 | 0.85 | GPBAR1 (0.69) | GPBAR1NR1H4SLC10A2PDE3ATBXA2R | |
| SCHEMBL15145513 | 0.85 | GPBAR1 (0.81) | GPBAR1NR1H4SLC10A2PDE3ATBXA2R | |
| SCHEMBL1656466 | 0.85 | GPBAR1 (0.81) | GPBAR1NR1H4SLC10A2PDE3ATBXA2R | |
| SCHEMBL16225956 | 0.84 | GPBAR1 (0.65) | GPBAR1NR1H4SLC10A2PDE3ATBXA2R | |
| SCHEMBL20963021 | 0.83 | GPBAR1 (0.82) | GPBAR1NR1H4SLC10A2PDE3ATBXA2R | |
| SCHEMBL20008824 | 0.82 | MAPT (0.62) | GPBAR1NR1H4SLC10A2PDE3ATBXA2R | |
| SCHEMBL20012664 | 0.82 | MAPT (0.62) | GPBAR1NR1H4SLC10A2PDE3ATBXA2R | |
| Lagodeoxycholate SCHEMBL23781785 | 0.81 | GPBAR1 (0.96) | GPBAR1NR1H4SLC10A2PDE3ATBXA2R | |
| Lagodeoxycholate SCHEMBL24032585 | 0.81 | GPBAR1 (1.00) | GPBAR1NR1H4SLC10A2PDE3ATBXA2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090232913-A1 | Composition for the Control of Cholesterol Levels | VANADIS BIOSCIENCE LTD. (NZ) | 2009-09-17 | — | — | US | claimed |
| US-20090232913-A1 | Composition for the Control of Cholesterol Levels | VANADIS BIOSCIENCE LTD. (NZ) | 2009-09-17 | — | — | US | disclosed |
| US-20090074895-A1 | COMPOSITION AND USES THEREOF | VANADIS BIOSCIENCE LTD (NZ) | 2009-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090232913-A1 | Composition for the Control of Cholesterol Levels | CETP, HMGCR, CYP46A1 | GPBAR1 96/4885NR1H4 12/4885SLC10A2 18/4885 |
| US-20090074895-A1 | COMPOSITION AND USES THEREOF | SLC5A2, SLC5A1, SLC10A1 | GPBAR1 97/4885NR1H4 9/4885SLC10A2 4/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.