Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INPP5D | Q92835 | 1/20 | 0.57 |
| ▸ | CDC25A | P30304 | 10/20 | 0.55 |
| ▸ | CDC25B | P30305 | 10/20 | 0.55 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1L1 | Q9UHC9 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7127648 | 0.88 | INPP5D (0.55) | INPP5DCDC25ACDC25BPLA2G1BUSP2 | |
| SCHEMBL7127645 | 0.88 | INPP5D (0.55) | INPP5DCDC25ACDC25BPLA2G1BUSP2 | |
| SCHEMBL18541413 | 0.78 | INPP5D (0.73) | INPP5DCDC25ACDC25BPLA2G1BUSP2 | |
| SCHEMBL6560618 | 0.78 | INPP5D (0.62) | INPP5DCDC25ACDC25BPLA2G1BUSP2 | |
| SCHEMBL6560622 | 0.78 | INPP5D (0.62) | INPP5DCDC25ACDC25BPLA2G1BUSP2 | |
| SCHEMBL30364762 | 0.76 | CDC25A (0.59) | INPP5DCDC25ACDC25BMEN1KMT2A | |
| SCHEMBL24103972 | 0.75 | INPP5D (0.64) | INPP5DCDC25ACDC25BPLA2G1BUSP2 | |
| SCHEMBL294537 | 0.75 | GPBAR1 (0.74) | CDC25ACDC25BMEN1KMT2ALMNA | |
| SCHEMBL11383608 | 0.75 | GPBAR1 (0.74) | CDC25ACDC25BMEN1KMT2ALMNA | |
| SCHEMBL16226084 | 0.75 | USP2 (0.52) | USP2MEN1KMT2ALMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140335050-A1 | METHODS, COMPOSITIONS, AND KITS FOR THE TREATMENT OF CANCER | THE GENERAL HOSPITAL CORPORATION (US) | 2014-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140335050-A1 | METHODS, COMPOSITIONS, AND KITS FOR THE TREATMENT OF CANCER | IL2RA, CD74, IL2 | INPP5D 4454/4885CDC25A 334/4885CDC25B 1240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.