SCHEMBL294537

SCHEMBL294537

CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3C(O)CC4CCCC[C@]4(C)[C@H]3CC[C@]12C

nearest known ligand 0.74

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ GPBAR1 Q8TDU6 10/20 0.74
▸ NR1H4 Q96RI1 7/20 0.74
▸ CDC25A P30304 1/20 0.63
▸ CDC25B P30305 1/20 0.63
▸ CYP8B1 Q9UNU6 1/20 0.60
▸ CYP2C19 P33261 2/20 0.57
▸ CYP2D6 P10635 1/20 0.57
▸ MEN1 O00255 2/20 0.57
▸ KMT2A Q03164 2/20 0.57
▸ ABCB11 O95342 2/20 0.57
▸ SLC10A2 Q12908 2/20 0.57
▸ LMNA P02545 1/20 0.57
▸ CHRM2 P08172 1/20 0.57
▸ ADRA2A P08913 1/20 0.57
▸ ADRA1A P35348 1/20 0.57
▸ TDP1 Q9NUW8 1/20 0.57
▸ ENPP2 Q13822 1/20 0.57
▸ SLC10A1 Q14973 1/20 0.57
▸ CISD1 Q9NZ45 1/20 0.57

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11383608 1.00 GPBAR1 (0.74) GPBAR1NR1H4CDC25ACDC25BCYP8B1
SCHEMBL19064984 0.91 GPBAR1 (0.78) GPBAR1NR1H4CYP2C19MEN1KMT2A
SCHEMBL17641310 0.90 GPBAR1 (0.72) GPBAR1NR1H4CYP2C19MEN1KMT2A
SCHEMBL15984655 0.89 GPBAR1 (0.77) GPBAR1NR1H4CYP2C19MEN1KMT2A
SCHEMBL13811560 0.89 GPBAR1 (0.77) GPBAR1NR1H4CYP2C19MEN1KMT2A
SCHEMBL23710531 0.89 NR1H4 (0.77) GPBAR1NR1H4CYP2C19MEN1KMT2A
SCHEMBL17303269 0.89 GPBAR1 (0.77) GPBAR1NR1H4CYP2C19MEN1KMT2A
SCHEMBL25926254 0.89 GPBAR1 (0.76) GPBAR1NR1H4CYP2C19MEN1KMT2A
SCHEMBL25926256 0.89 GPBAR1 (0.76) GPBAR1NR1H4CYP2C19MEN1KMT2A
SCHEMBL30532089 0.89 GPBAR1 (0.67) GPBAR1NR1H4CYP2C19MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 268 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114942292-B Method for detecting content of plant sterol substances in blood based on liquid chromatography-tandem mass spectrometry technology 中国医学科学院阜外医院 2023-09-12 — — CN claimed
WO-2023140722-A1 TOMATOES CONTAINING HIGH LEVELS OF 7-DEHYDROCHOLESTEROL AND PREPARATION METHOD THEREFOR (주)지플러스생명과학 2023-07-27 — — WO claimed
US-10308971-B2 Microorganism for expressing a human membrane protein NOVOZYMES A/S (DK) 2019-06-04 — — US claimed
US-20180171374-A1 Microorganism For Expressing A Human Membrane Protein NOVOZYMES A/S (DK) 2018-06-21 — — US claimed
US-9920348-B2 Microorganism for expressing a human membrane protein NOVOZYMES A/S (DK) 2018-03-20 — — US claimed
US-9598710-B2 Genetically modified organism for the production of lipids ORGANOBALANCE GMBH (DE) 2017-03-21 — — US claimed
US-20150093781-A1 MICROORGANISM FOR EXPRESSING A HUMAN MEMBRANE PROTEIN NOVOZYMES A/S (DK) 2015-04-02 — — US claimed
US-20150024009-A1 GENETICALLY MODIFIED ORGANISM FOR THE PRODUCTION OF LIPIDS ORGANOBALANCE GMBH (DE) 2015-01-22 — — US claimed
US-8841114-B2 Genetically modified organism for the production of lipids ORGANOBALANCE GMBH (DE) 2014-09-23 — — US claimed
EP-2586859-A1 Genetically modified organisms for the production of lipids OrganoBalance GmbH (DE) 2013-05-01 — — EP claimed
WO-2007050554-A2 METHODS FOR IDENTIFYING COMPOUNDS THAT MODULATE PHB DOMAIN PROTEIN ACTIVITY AND COMPOSITIONS THEREOF THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) 2007-05-03 — — WO claimed
EP-1663327-A1 MOISTURIZING AND LUBRICATING COMPOSITIONS Kimberly-Clark Worldwide, Inc. (US) 2006-06-07 — — EP claimed
US-20050101927-A1 Absorbent products comprising a moisturizing and lubricating composition KIMBERLY-CLARK WORLDWIDE, INC. 2005-05-12 — — US claimed
WO-2005034905-A1 TISSUE PRODUCTS COMPRISING A MOISTURIZING AND LUBRICATING COMPOSITION KIMBERLY-CLARK WORLDWIDE, INC. (US) 2005-04-21 — — WO claimed
WO-2005035011-A1 MOISTURIZING AND LUBRICATING COMPOSITIONS KIMBERLY-CLARK WORLDWIDE, INC. (US) 2005-04-21 — — WO claimed
WO-2005035013-A1 ABSORBENT PRODUCTS COMPRISING A MOISTURIZING AND LUBRICATING COMPOSITIONS KIMBERLY-CLARK WORLDWIDE, INC. (US) 2005-04-21 — — WO claimed
US-20050058693-A1 Tissue products comprising a moisturizing and lubricating composition KIMBERLY-CLARK WORLDWIDE, INC. 2005-03-17 — — US claimed
US-20050058674-A1 Moisturizing and lubricating compositions KIMBERLY-CLARK WORLDWIDE, INC. 2005-03-17 — — US claimed
EP-0070588-B1 METHOD OF PREPARING 1-ALPHA-HYDROXYVITAMIN D AND 1-ALPHA-HYDROXY-PREVITAMIN D COMPOUNDS, AND ADDUCT OF A PREVITAMIN D OR TACHYSTEROL COMPOUND WITH A SUITABLE DIENOPHILE DUPHAR INTERNATIONAL RESEARCH B.V (NL) 1986-05-07 — — EP claimed
US-4388242-A Method of production of vitamin-D CANADIAN PATENTS & DEVELOPMENT LIMITED (CA) 1983-06-14 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050058693-A1 Tissue products comprising a moisturizing and lubricating composition MUC1, CUTA, COL14A1 GPBAR1 4724/4885NR1H4 4678/4885CDC25A 789/4885
US-20050058674-A1 Moisturizing and lubricating compositions CUTA, DSG1, MUC1 GPBAR1 4031/4885NR1H4 4126/4885CDC25A 958/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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