Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.34 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.33 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.32 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.31 |
| ▸ | NT5E | P21589 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14418608 | 1.00 | LMNA (0.34) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL9964282 | 0.89 | LMNA (0.47) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL3691247 | 0.89 | LMNA (0.47) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL14946323 | 0.89 | LMNA (0.47) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL15765583 | 0.89 | LMNA (0.47) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL12404744 | 0.89 | LMNA (0.47) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL27056652 | 0.89 | LMNA (0.47) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL27065056 | 0.89 | LMNA (0.47) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL20215740 | 0.86 | P2RY6 (0.34) | LMNATHRBMTORMDM2NCOA1 | |
| SCHEMBL1937265 | 0.86 | P2RY6 (0.34) | LMNATHRBMTORMDM2NCOA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8884001-B2 | Preparation of intermediates useful in the synthesis of 2′-cyano-2′-deoxy-N4-palmi-toyl-1-β-D-arabinofuranosylcytosine | CYCLACEL LIMITED (GB) | 2014-11-11 | — | — | US | disclosed |