Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 13/20 | 0.62 |
| ▸ | HTR2A | P28223 | 11/20 | 0.62 |
| ▸ | HTR1A | P08908 | 10/20 | 0.62 |
| ▸ | HTR7 | P34969 | 7/20 | 0.62 |
| ▸ | HTR2C | P28335 | 3/20 | 0.62 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.62 |
| ▸ | HTR2B | P41595 | 2/20 | 0.62 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.62 |
| ▸ | HRH1 | P35367 | 2/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.62 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.62 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.62 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.62 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.62 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.62 |
| ▸ | DRD1 | P21728 | 1/20 | 0.62 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.62 |
| ▸ | ACHE | P22303 | 1/20 | 0.62 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.62 |
| ▸ | PDE4A | P27815 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12445891 | 1.00 | DRD2 (0.62) | DRD2HTR2AHTR1AHTR7HTR2C | |
| SCHEMBL2540314 | 0.79 | DRD2 (0.63) | DRD2HTR2AHTR1AHTR7HTR2C | |
| SCHEMBL2545280 | 0.78 | DRD2 (0.66) | DRD2HTR2AHTR1AHTR7HTR2C | |
| Lurasidone SCHEMBL2587434 | 0.77 | DRD2 (1.00) | DRD2HTR2AHTR1AHTR7HTR2C | |
| Lurasidone SCHEMBL19678283 | 0.77 | DRD2 (1.00) | DRD2HTR2AHTR1AHTR7HTR2C | |
| Lurasidone SCHEMBL2120201 | 0.77 | DRD2 (1.00) | DRD2HTR2AHTR1AHTR7HTR2C | |
| Lurasidone SCHEMBL10034018 | 0.77 | DRD2 (1.00) | DRD2HTR2AHTR1AHTR7HTR2C | |
| Lurasidone SCHEMBL677525 | 0.77 | DRD2 (1.00) | DRD2HTR2AHTR1AHTR7HTR2C | |
| Lurasidone SCHEMBL21702794 | 0.77 | DRD2 (1.00) | DRD2HTR2AHTR1AHTR7HTR2C | |
| Lurasidone SCHEMBL16804108 | 0.77 | DRD2 (1.00) | DRD2HTR2AHTR1AHTR7HTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8883794-B2 | Pharmaceutical composition | SUMITOMO DAINIPPON PHARMA CO., LTD. (JP) | 2014-11-11 | — | — | US | disclosed |