Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 5/20 | 0.54 |
| ▸ | HTR1A | P08908 | 10/20 | 0.51 |
| ▸ | HTR7 | P34969 | 10/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29195203 | 0.98 | DPP4 (0.53) | DPP4HTR1AHTR7 | |
| SCHEMBL14463150 | 0.89 | DPP4 (0.51) | DPP4HTR1AHTR7 | |
| SCHEMBL3744849 | 0.87 | DPP4 (0.46) | DPP4HTR1AHTR7 | |
| SCHEMBL30182974 | 0.86 | DPP4 (0.48) | DPP4 | |
| SCHEMBL5035727 | 0.86 | ACE (0.59) | — | |
| SCHEMBL5035730 | 0.86 | ACE (0.59) | — | |
| SCHEMBL5033213 | 0.86 | ACE (0.59) | — | |
| SCHEMBL30182675 | 0.85 | DPP4 (0.47) | DPP4HTR1AHTR7 | |
| SCHEMBL30182755 | 0.85 | DPP4 (0.47) | DPP4HTR1AHTR7 | |
| SCHEMBL30182795 | 0.85 | DPP4 (0.47) | DPP4HTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1879607-B1 | HCV NS3 PROTEASE INHIBITORS | MERCK SHARP & DOHME (US) | 2014-11-12 | — | — | EP | disclosed |