Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 5/20 | 0.46 |
| ▸ | HTR1A | P08908 | 7/20 | 0.44 |
| ▸ | HTR7 | P34969 | 7/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29195203 | 0.89 | DPP4 (0.53) | DPP4HTR1AHTR7 | |
| SCHEMBL3745290 | 0.88 | ACE (0.53) | HAO1 | |
| SCHEMBL16229682 | 0.87 | DPP4 (0.54) | DPP4HTR1AHTR7 | |
| SCHEMBL3747517 | 0.85 | LMNA (0.47) | DPP4HAO1 | |
| SCHEMBL6016860 | 0.85 | ACE (0.51) | HAO1 | |
| SCHEMBL3731038 | 0.85 | LMNA (0.47) | DPP4HAO1 | |
| SCHEMBL30183089 | 0.84 | DPP4 (0.47) | DPP4HTR1AHTR7 | |
| SCHEMBL30182675 | 0.84 | DPP4 (0.47) | DPP4HTR1AHTR7 | |
| SCHEMBL30182795 | 0.84 | DPP4 (0.47) | DPP4HTR1AHTR7 | |
| SCHEMBL30182755 | 0.84 | DPP4 (0.47) | DPP4HTR1AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100280034-A1 | Modulation of pathogenicity | QUONOVA, LLC | 2010-11-04 | — | — | US | disclosed |
| US-7338969-B2 | Modulation of pathogenicity | QUONOVA, LLC (US) | 2008-03-04 | — | — | US | disclosed |
| US-20070208012-A1 | Modulation of Pathogenicity | QUONOVA, LLC | 2007-09-06 | — | — | US | disclosed |
| US-20070203128-A1 | Modulation of Pathogenicity | QUONOVA, LLC | 2007-08-30 | — | — | US | disclosed |
| US-20070196340-A1 | Modulation of Pathogenicity | QUONOVA, LLC | 2007-08-23 | — | — | US | disclosed |
| US-20070197492-A1 | Modulation of Pathogenicity | QUONOVA, LLC | 2007-08-23 | — | — | US | disclosed |
| US-20070184014-A1 | Modulation of Pathogenicity | QUONOVA, LLC | 2007-08-09 | — | — | US | disclosed |
| US-20070093534-A1 | Modulation of Pathogenicity | QUONOVA, LLC | 2007-04-26 | — | — | US | disclosed |
| EP-1622890-A2 | BLOCKERS OF THE QUORUM SENSING SYSTEM OF GRAM-NEGATIVE BACTERIA | 4SC AG (DE) | 2006-02-08 | — | — | EP | disclosed |
| US-20040235914-A1 | Modulation of pathogenicity | 4 SC AG (DE) | 2004-11-25 | — | — | US | disclosed |
| WO-2004099175-A2 | BLOCKERS OF THE QUORUM SENSING SYSTEM OF GRAM-NEGATIVE BACTERIA | 4SC AG (DE) | 2004-11-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070197492-A1 | Modulation of Pathogenicity | ANTXR2, Q6ZSR9, PGLS | DPP4 2970/4885HTR1A 3735/4885HTR7 3866/4885 |
| US-20070203128-A1 | Modulation of Pathogenicity | ANTXR2, Q6ZSR9, PGLS | DPP4 2970/4885HTR1A 3735/4885HTR7 3866/4885 |
| US-20070093534-A1 | Modulation of Pathogenicity | NR1H4, NR1I3, NR1H2 | DPP4 4773/4885HTR1A 1996/4885HTR7 1787/4885 |
| US-20040235914-A1 | Modulation of pathogenicity | Q6ZSR9, CCL11, CFH | DPP4 4426/4885HTR1A 3332/4885HTR7 2144/4885 |
| US-20070208012-A1 | Modulation of Pathogenicity | ANTXR2, Q6ZSR9, PGLS | DPP4 2970/4885HTR1A 3735/4885HTR7 3866/4885 |
| US-20100280034-A1 | Modulation of pathogenicity | NR1H4, NR1I3, NR1H2 | DPP4 4773/4885HTR1A 1996/4885HTR7 1787/4885 |
| US-20070184014-A1 | Modulation of Pathogenicity | ANTXR2, Q6ZSR9, PGLS | DPP4 2970/4885HTR1A 3735/4885HTR7 3866/4885 |
| US-20070196340-A1 | Modulation of Pathogenicity | NR1H4, NR1I3, NR1H2 | DPP4 4773/4885HTR1A 1996/4885HTR7 1787/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.