Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.37 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18784406 | 0.98 | ALDH1A1 (0.45) | ALDH1A1ALDH3A1PTGS2LMNAAPOBEC3A | |
| SCHEMBL18784441 | 0.98 | ALDH1A1 (0.45) | ALDH1A1ALDH3A1PTGS2LMNAAPOBEC3A | |
| SCHEMBL18784571 | 0.98 | ALDH1A1 (0.45) | ALDH1A1ALDH3A1PTGS2LMNAAPOBEC3A | |
| SCHEMBL18784565 | 0.98 | ALDH1A1 (0.45) | ALDH1A1ALDH3A1PTGS2LMNAAPOBEC3A | |
| SCHEMBL18784568 | 0.98 | ALDH1A1 (0.45) | ALDH1A1ALDH3A1PTGS2LMNAAPOBEC3A | |
| SCHEMBL18784425 | 0.98 | ALDH1A1 (0.45) | ALDH1A1ALDH3A1PTGS2LMNAAPOBEC3A | |
| SCHEMBL18784554 | 0.98 | ALDH1A1 (0.45) | ALDH1A1ALDH3A1PTGS2LMNAAPOBEC3A | |
| SCHEMBL18784618 | 0.98 | ALDH1A1 (0.45) | ALDH1A1ALDH3A1PTGS2LMNAAPOBEC3A | |
| SCHEMBL8557615 | 0.94 | ALDH1A1 (0.48) | ALDH1A1ALDH3A1PTGS2LMNAAPOBEC3A | |
| SCHEMBL1622699 | 0.86 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3162799-B1 | FLUOROALKYLATING AGENT | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2021-03-10 | — | — | EP | disclosed |
| US-10696640-B2 | Fluoroalkylating agent | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2020-06-30 | — | — | US | disclosed |
| US-20190233380-A1 | FLUOROALKYLATING AGENT | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2019-08-01 | — | — | US | disclosed |
| US-10308613-B2 | Fluoroalkylating agent | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2019-06-04 | — | — | US | disclosed |
| US-20170197920-A1 | FLUOROALKYLATING AGENT | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2017-07-13 | — | — | US | disclosed |
| EP-3162799-A1 | FLUOROALKYLATING AGENT | Ihara Chemical Industry Co., Ltd. (JP) | 2017-05-03 | — | — | EP | disclosed |
| CN-105606414-A | A set of wire spectrum standard samples and preparation method | SHANDONG METALLURGICAL SCIENCE RES INST | 2016-05-25 | — | — | CN | disclosed |
| US-7928264-B2 | Aminoalcohol derivatives | ASTELLAS PHARMA INC. (JP) | 2011-04-19 | — | — | US | disclosed |
| CN-101039902-B | Aminoalcohol derivatives | ASTELLAS PHARMA INC | 2010-11-10 | — | — | CN | disclosed |
| EP-1791811-B1 | AMINOALCOHOL DERIVATIVES | ASTELLAS PHARMA INC (JP) | 2009-12-23 | — | — | EP | disclosed |
| US-20080039506-A1 | Aminoalcohol Derivatives | ASTELLAS PHARMA INC. (JP) | 2008-02-14 | — | — | US | disclosed |
| CN-101039902-A | Aminoalcohol derivatives | ASTELLAS PHARMA INC (JP) | 2007-09-19 | — | — | CN | disclosed |
| EP-1791811-A1 | AMINOALCOHOL DERIVATIVES | Astellas Pharma Inc. (JP) | 2007-06-06 | — | — | EP | disclosed |
| WO-2006033446-A1 | AMINOALCOHOL DERIVATIVES | ASTELLAS PHARMA INC. (JP) | 2006-03-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10308613-B2 | Fluoroalkylating agent | AFF1, AFF4, AFF2 | ALDH1A1 2072/4885ALDH3A1 2205/4885PTGS2 4696/4885 |
| US-10696640-B2 | Fluoroalkylating agent | AFF1, AFF4, AFF2 | ALDH1A1 2072/4885ALDH3A1 2205/4885PTGS2 4696/4885 |
| US-20190233380-A1 | FLUOROALKYLATING AGENT | AFF1, AFF4, AFF2 | ALDH1A1 2072/4885ALDH3A1 2205/4885PTGS2 4696/4885 |
| US-20170197920-A1 | FLUOROALKYLATING AGENT | AFF1, AFF4, AFF2 | ALDH1A1 2072/4885ALDH3A1 2205/4885PTGS2 4696/4885 |
| US-20080039506-A1 | Aminoalcohol Derivatives | HRH4, HRH2, CBR3 | ALDH1A1 363/4885ALDH3A1 189/4885PTGS2 1023/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.