Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | NAAA | Q02083 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.57 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.56 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | CA9 | Q16790 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11337226 | 0.98 | GAA (0.65) | GAANAAALMNAPOLBHDAC1 | |
| Hydrochloric Acid SCHEMBL3581933 | 0.98 | GAA (0.65) | GAANAAALMNAPOLBHDAC1 | |
| Hydrochloric Acid SCHEMBL27504812 | 0.98 | GAA (0.65) | GAANAAALMNAPOLBHDAC1 | |
| SCHEMBL11337298 | 0.98 | GAA (0.65) | GAANAAALMNAPOLBHDAC1 | |
| SCHEMBL11335914 | 0.98 | GAA (0.65) | GAANAAALMNAPOLBHDAC1 | |
| Dimethylamine SCHEMBL7749429 | 0.96 | GAA (0.63) | GAANAAALMNAPOLBHDAC1 | |
| Benzophenone SCHEMBL28338522 | 0.94 | GAA (0.61) | GAANAAALMNAPOLBHDAC1 | |
| SCHEMBL27934347 | 0.94 | GAA (0.61) | GAANAAALMNAPOLBHDAC1 | |
| SCHEMBL4050062 | 0.94 | GAA (0.61) | GAANAAALMNAPOLBHDAC1 | |
| SCHEMBL13753313 | 0.92 | ALDH1A1 (0.62) | GAANAAALMNAPOLBHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1389 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12492193-B2 | Pyrazole derivatives for the treatment of cystic fibrosis | FONDAZIONE INSTITUTO ITALIANO DI TECNOLOGIA (IT) | 2025-12-09 | — | — | US | claimed |
| EP-3310822-B1 | PROCATALYST FOR POLYMERIZATION OF OLEFINS COMPRISING AN AMINOBENZOATE INTERNAL DONOR AND A 1,3-DIETHER INTERNAL DONOR IN A SPECIFIC RATIO | SABIC GLOBAL TECHNOLOGIES BV (NL) | 2023-10-11 | — | — | EP | claimed |
| US-20230212157-A1 | PYRAZOLE DERIVATIVES FOR THE TREATMENT OF CYSTIC FIBROSIS | ISTITUTO GIANNINA GASLINI (IT) | 2023-07-06 | — | — | US | claimed |
| WO-2023103261-A1 | CRYSTAL FORM B OF ETHYL 2-CYANO-3-AMINO-3-PHENYLACRYLATE, PREPARATION METHOD, AND APPLICATION | 江苏省农药研究所股份有限公司 | 2023-06-15 | — | — | WO | claimed |
| CN-115772072-A | Preparation method of m-phenoxy benzaldehyde | 上海筑裕新材料科技有限公司 | 2023-03-10 | — | — | CN | claimed |
| US-11597723-B2 | Pyrazole derivatives for the treatment of cystic fibrosis | FONDAZIONE ISTITUTO ITALIANO DI TECHNOLOGIA (IT) | 2023-03-07 | — | — | US | claimed |
| CN-115677696-A | Preparation method of benzonaphthyridine derivative | 华侨大学 | 2023-02-03 | — | — | CN | claimed |
| CN-112294816-B | Application of ethyl benzamide compound in preparation of local anesthetic | 四川大学华西医院 | 2021-07-30 | — | — | CN | claimed |
| CN-112294816-A | Application of ethyl benzamide compound in preparation of local anesthetic | 四川大学华西医院 | 2021-02-02 | — | — | CN | claimed |
| EP-3703692-A1 | NOVEL SUBSTITUTED TETRAHYDROQUINOLIN COMPOUNDS AS INDOLEAMINE 2,3-DIOXYGENASE (IDO) INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2020-09-09 | — | — | EP | claimed |
| US-5393760-A | Cardiovascular disorders, antitumor agents | HOFFMANN-LA ROCHE INC. (US) | 1995-02-28 | — | — | US | claimed |
| EP-0468231-B1 | Guanidins | HOFFMANN LA ROCHE (CH) | 1994-09-21 | — | — | EP | claimed |
| US-5039735-A | Hydrolyzable silane or siloxane compound, filler, curing catalyst, amide; readily releasable | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1991-08-13 | — | — | US | claimed |
| EP-0287421-B1 | PROCESS FOR THE CYCLIC PRODUCTION OF HYDROGEN PEROXIDE | ELF ATOCHEM S.A. (FR) | 1991-06-05 | — | — | EP | claimed |
| EP-0287421-A1 | Process for the cyclic production of hydrogen peroxide | ELF ATOCHEM S.A. (FR) | 1988-10-19 | — | — | EP | claimed |
| US-4647625-A | Process for modifying conjugated diene polymers | NIPPON ZEON CO., LTD. (JP) | 1987-03-03 | — | — | US | claimed |
| EP-0052442-B1 | HETEROCYCLIC COMPOUNDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-09-11 | — | — | EP | claimed |
| US-4503054-A | VASODILATORS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-03-05 | — | — | US | claimed |
| US-4431478-A | Etching agent for polyimide type resins and process for etching polyimide type resins with the same | SUMITOMO BAKELITE CO. LTD. (JP) | 1984-02-14 | — | — | US | claimed |
| EP-0052442-A1 | Heterocyclic compounds | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-05-26 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230212157-A1 | PYRAZOLE DERIVATIVES FOR THE TREATMENT OF CYSTIC FIBROSIS | CFTR, ABCC5, ABCC1 | GAA 952/4885NAAA 3583/4885LMNA 4394/4885 |
| US-12492193-B2 | Pyrazole derivatives for the treatment of cystic fibrosis | CFTR, ABCC5, ABCC1 | GAA 952/4885NAAA 3583/4885LMNA 4394/4885 |
| US-11597723-B2 | Pyrazole derivatives for the treatment of cystic fibrosis | CFTR, ABCC5, ABCC3 | GAA 970/4885NAAA 3575/4885LMNA 4357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.