Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Methacrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SLC13A3 | Q8WWT9 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methacrylic Acid SCHEMBL1623992 | 0.95 | CASP1 (0.52) | CASP1CA1TDP1FFAR3HDAC3 | |
| Methacrylic Acid SCHEMBL1623028 | 0.95 | CASP1 (0.52) | CASP1CA1TDP1FFAR3HDAC3 | |
| Methacrylic Acid SCHEMBL7192219 | 0.87 | CASP1 (0.55) | CASP1CA1TDP1FFAR3HDAC3 | |
| Methacrylic Acid SCHEMBL7192124 | 0.82 | CASP1 (0.55) | CASP1CA1TDP1FFAR3HDAC3 | |
| Methacrylic Acid SCHEMBL1622456 | 0.82 | TDP1 (0.38) | CA1TDP1FFAR3HDAC3HDAC1 | |
| Methacrylic Acid SCHEMBL7191720 | 0.82 | CASP1 (0.55) | CASP1CA1TDP1FFAR3HDAC3 | |
| Methacrylic Acid SCHEMBL1621313 | 0.81 | CA1 (0.53) | CA1TDP1FFAR3CA4 | |
| Methacrylic Acid SCHEMBL1623920 | 0.80 | TDP1 (0.41) | CA1TDP1FFAR3HDAC3HDAC1 | |
| Methacrylic Acid SCHEMBL2233282 | 0.78 | — | — | |
| Methacrylic Acid SCHEMBL5879023 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7928175-B2 | Antifouling paint composition | MITSUBISHI RAYON CO., LTD. (JP) | 2011-04-19 | — | — | US | disclosed |
| US-20060258772-A1 | Antifouling paint composition | MITSUBISHI RAYON CO. LTD. (JP) | 2006-11-16 | — | — | US | disclosed |