Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 16/20 | 0.83 |
| ▸ | MET | P08581 | 8/20 | 0.78 |
| ▸ | EGFR | P00533 | 6/20 | 0.78 |
| ▸ | SRC | P12931 | 4/20 | 0.78 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1555452 | 0.94 | AXL (0.86) | AXLMETEGFRSRC | |
| SCHEMBL1555944 | 0.94 | AXL (0.86) | AXLMETEGFRSRC | |
| SCHEMBL1555578 | 0.92 | AXL (0.82) | AXLMETEGFRSRC | |
| SCHEMBL1591773 | 0.92 | AXL (0.82) | AXLMETEGFRSRC | |
| SCHEMBL1591758 | 0.92 | AXL (0.82) | AXLMETEGFRSRC | |
| SCHEMBL16232879 | 0.91 | AXL (0.81) | AXLMETEGFRSRC | |
| SCHEMBL1591192 | 0.91 | AXL (1.00) | AXLMETEGFRSRC | |
| SCHEMBL1591619 | 0.91 | AXL (0.86) | AXLMETEGFRSRC | |
| SCHEMBL1591781 | 0.90 | AXL (0.80) | AXLMETEGFRSRC | |
| SCHEMBL1591716 | 0.90 | AXL (0.84) | AXLMETEGFRSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140336191-A1 | QUINOLINYLOXYPHENYLSULFONAMIDES | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG DER WISSENSCHAFTEN E.V. (DE) | 2014-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140336191-A1 | QUINOLINYLOXYPHENYLSULFONAMIDES | TP53, AQP1, KRAS | AXL 4326/4885MET 2187/4885EGFR 2891/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.