Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.46 |
| ▸ | CKS1B | P61024 | 2/20 | 0.42 |
| ▸ | SKP1 | P63208 | 2/20 | 0.42 |
| ▸ | SKP2 | Q13309 | 2/20 | 0.42 |
| ▸ | DTYMK | P23919 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.41 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12740840 | 0.88 | GPR119 (0.65) | GPR119MAPTCKS1BSKP1SKP2 | |
| SCHEMBL12740856 | 0.86 | GPR119 (0.60) | GPR119MAPTCKS1BSKP1SKP2 | |
| SCHEMBL20129625 | 0.85 | GPR119 (0.57) | GPR119POLBACHECKS1BSKP1 | |
| SCHEMBL23108171 | 0.81 | GPR119 (0.52) | GPR119POLBMAPTACHECYP11B2 | |
| SCHEMBL38661127 | 0.81 | GPR119 (0.49) | GPR119POLBMAPTCYP11B2 | |
| SCHEMBL14892711 | 0.79 | GPR119 (0.53) | GPR119POLBMAPTACHEDTYMK | |
| SCHEMBL24349618 | 0.78 | GPR119 (0.52) | GPR119MAPTCKS1BSKP1SKP2 | |
| SCHEMBL12964579 | 0.77 | GPR119 (0.77) | GPR119POLBMAPTACHECKS1B | |
| SCHEMBL24349617 | 0.77 | GPR119 (0.61) | GPR119 | |
| SCHEMBL24349229 | 0.77 | GPR119 (0.52) | GPR119POLBMAPTCKS1BSKP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014184248-A2 | TRPA1 ANTAGONIST COMPOUNDS | Acturum Life Science AB (SE) | 2014-11-20 | — | — | WO | disclosed |