Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.49 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16236929 | 0.80 | DAO (0.53) | KMT2AMEN1GAA | |
| SCHEMBL4544349 | 0.80 | BAZ2B (0.62) | BAZ2BBAZ2AKMT2AMEN1GAA | |
| SCHEMBL16236626 | 0.80 | BAZ2B (0.48) | BAZ2BBAZ2AKMT2AMEN1GAA | |
| SCHEMBL16364739 | 0.78 | BAZ2B (0.56) | BAZ2BBAZ2AKMT2AMEN1GAA | |
| SCHEMBL16237105 | 0.77 | KMT2A (0.44) | BAZ2BBAZ2AKMT2AMEN1GAA | |
| SCHEMBL3113139 | 0.77 | BAZ2B (0.54) | BAZ2BBAZ2AKMT2AMEN1GAA | |
| Hydrochloric Acid SCHEMBL7377017 | 0.76 | BAZ2B (0.53) | BAZ2BBAZ2AKMT2AMEN1GAA | |
| Hydrochloric Acid SCHEMBL5546234 | 0.76 | BAZ2B (0.53) | BAZ2BBAZ2AKMT2AMEN1GAA | |
| SCHEMBL9192084 | 0.76 | BAZ2B (0.53) | BAZ2BBAZ2AKMT2AMEN1GAA | |
| SCHEMBL9908199 | 0.76 | BAZ2B (0.57) | BAZ2BBAZ2AKMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4028395-A1 | SULFONAMIDE COMPOUNDS AND THE USE THEREOF IN THE TREATMENT OF CANCER | Trobio Therapeutics Pty Ltd (AU) | 2022-07-20 | — | — | EP | disclosed |
| WO-2021072487-A1 | SULFONAMIDE COMPOUNDS AND THE USE THEREOF IN THE TREATMENT OF CANCER | TroBio Therapeutics Pty Ltd (AU) | 2021-04-22 | — | — | WO | disclosed |
| EP-3102572-A1 | SULPHAMOYLPYRROLAMIDE DERIVATIVES AND THE USE THEREOF AS MEDICAMENTS FOR THE TREATMENT OF HEPATITIS B | Janssen Sciences Ireland UC (IE) | 2016-12-14 | — | — | EP | disclosed |
| EP-2997011-A1 | SULPHAMOYLPYRROLAMIDE DERIVATIVES AND THE USE THEREOF AS MEDICAMENTS FOR THE TREATMENT OF HEPATITIS B | Janssen Sciences Ireland UC (IE) | 2016-03-23 | — | — | EP | disclosed |
| WO-2015118057-A1 | SULPHAMOYLPYRROLAMIDE DERIVATIVES AND THE USE THEREOF AS MEDICAMENTS FOR THE TREATMENT OF HEPATITIS B | JANSSEN SCIENCES IRELAND UC (IE) | 2015-08-13 | — | — | WO | disclosed |
| WO-2014184350-A1 | SULPHAMOYLPYRROLAMIDE DERIVATIVES AND THE USE THEREOF AS MEDICAMENTS FOR THE TREATMENT OF HEPATITIS B | JANSSEN R&D IRELAND (IE) | 2014-11-20 | — | — | WO | disclosed |