Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 12/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | TOP1 | P11387 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16236150 | 0.90 | KMT2A (0.52) | MAPTKMT2AMEN1SMN1; SMN2POLB | |
| SCHEMBL16239375 | 0.87 | ELANE (0.47) | ELANEMAPT | |
| SCHEMBL16236564 | 0.84 | KMT2A (0.49) | MAPTKMT2AMEN1SMN1; SMN2POLB | |
| SCHEMBL16237221 | 0.84 | PTPN1 (0.51) | ELANEMAPTKMT2AMEN1SMN1; SMN2 | |
| SCHEMBL16236624 | 0.83 | KMT2A (0.47) | MAPTKMT2AMEN1SMN1; SMN2POLB | |
| SCHEMBL15548022 | 0.82 | ELANE (0.66) | ELANEMAPTKMT2AMEN1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL16237107 | 0.82 | POLB (0.47) | MAPTKMT2AMEN1SMN1; SMN2POLB | |
| Hydrochloric Acid SCHEMBL16237108 | 0.82 | KMT2A (0.46) | MAPTKMT2AMEN1SMN1; SMN2POLB | |
| SCHEMBL16239270 | 0.81 | ELANE (0.42) | ELANEMAPTKMT2A | |
| SCHEMBL16236329 | 0.81 | PTPN1 (0.43) | ELANEKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2997050-B1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA SRL (IT) | 2018-01-17 | — | — | EP | disclosed |
| US-9714303-B2 | Catalyst components for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2017-07-25 | — | — | US | disclosed |
| US-20160115261-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia, s.r.l. (IT) | 2016-04-28 | — | — | US | disclosed |
| EP-2997050-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia S.r.l. (IT) | 2016-03-23 | — | — | EP | disclosed |
| WO-2014184171-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2014-11-20 | — | — | WO | disclosed |
| EP-2803678-A1 | Catalyst components for the polymerization of olefins | Basell Poliolefine Italia S.r.l. (IT) | 2014-11-19 | — | — | EP | disclosed |