Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 15/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16239270 | 0.93 | ELANE (0.42) | ELANELMNAALDH1A1CYP3A4HIF1A | |
| SCHEMBL16236329 | 0.93 | PTPN1 (0.43) | ELANELMNAALDH1A1CYP3A4HIF1A | |
| SCHEMBL16236717 | 0.92 | ELANE (0.41) | ELANELMNAALDH1A1CYP3A4HIF1A | |
| Hydrochloric Acid SCHEMBL16237201 | 0.91 | ELANE (0.41) | ELANELMNAALDH1A1CYP3A4HIF1A | |
| Hydrochloric Acid SCHEMBL16237202 | 0.91 | ELANE (0.41) | ELANELMNAALDH1A1CYP3A4HIF1A | |
| Hydrochloric Acid SCHEMBL16237049 | 0.88 | ELANE (0.39) | ELANELMNAALDH1A1CYP3A4HIF1A | |
| SCHEMBL16236575 | 0.88 | TYMS (0.40) | ELANELMNAALDH1A1CYP3A4HIF1A | |
| SCHEMBL16237045 | 0.87 | ELANE (0.50) | ELANEMAPT | |
| SCHEMBL16237053 | 0.85 | MEN1 (0.44) | ELANELMNAALDH1A1CYP3A4HIF1A | |
| SCHEMBL16236658 | 0.84 | KMT2A (0.44) | ELANELMNAALDH1A1CYP3A4HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2997050-B1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | BASELL POLIOLEFINE ITALIA SRL (IT) | 2018-01-17 | — | — | EP | disclosed |
| US-9714303-B2 | Catalyst components for the polymerization of olefins | BASELL POLIOLEFINE ITALIA S.R.L. (IT) | 2017-07-25 | — | — | US | disclosed |
| US-20160115261-A1 | CATALYST COMPONENTS FOR THE POLYMERIZATION OF OLEFINS | Basell Poliolefine Italia, s.r.l. (IT) | 2016-04-28 | — | — | US | disclosed |
| EP-2803678-A1 | Catalyst components for the polymerization of olefins | Basell Poliolefine Italia S.r.l. (IT) | 2014-11-19 | — | — | EP | disclosed |