Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Benzylimidazole. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 16/20 | 0.96 |
| ▸ | CYP11B2 | P19099 | 13/20 | 0.96 |
| ▸ | CYP19A1 | P11511 | 6/20 | 0.96 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.96 |
| ▸ | POLB | P06746 | 1/20 | 0.96 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.96 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.96 |
| ▸ | MAPT | P10636 | 1/20 | 0.96 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.96 |
| ▸ | QPCT | Q16769 | 1/20 | 0.96 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.96 |
| ▸ | QPCTL | Q9NXS2 | 1/20 | 0.96 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.77 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.67 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzylimidazole SCHEMBL414 | 0.98 | CYP11B1 (1.00) | CYP11B1CYP11B2CYP19A1CYP1A2POLB | |
| SCHEMBL22063900 | 0.98 | CYP11B1 (1.00) | CYP11B1CYP11B2CYP19A1CYP1A2POLB | |
| Benzylimidazole SCHEMBL31453527 | 0.96 | CYP11B1 (0.96) | CYP11B1CYP11B2CYP19A1CYP1A2POLB | |
| Benzylimidazole SCHEMBL29239318 | 0.96 | CYP11B1 (0.96) | CYP11B1CYP11B2CYP19A1CYP1A2POLB | |
| Benzylimidazole SCHEMBL3786782 | 0.96 | CYP11B1 (0.96) | CYP11B1CYP11B2CYP19A1CYP1A2POLB | |
| Benzylimidazole SCHEMBL411827 | 0.96 | CYP11B1 (0.96) | CYP11B1CYP11B2CYP19A1CYP1A2POLB | |
| Benzylimidazole SCHEMBL27803894 | 0.92 | CYP11B1 (0.89) | CYP11B1CYP11B2CYP19A1CYP1A2POLB | |
| Benzylimidazole SCHEMBL28764644 | 0.91 | CYP11B1 (0.86) | CYP11B1CYP11B2CYP19A1CYP1A2POLB | |
| Benzylimidazole SCHEMBL27535101 | 0.91 | CYP11B1 (0.86) | CYP11B1CYP11B2CYP19A1CYP1A2POLB | |
| Benzylimidazole SCHEMBL28970402 | 0.89 | CYP11B1 (0.83) | CYP11B1CYP11B2CYP19A1CYP1A2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107427869-A | Ash processing is with immobilization of heavy metals agent and uses its grey processing method | 栗田工业株式会社 | 2017-12-01 | — | — | CN | disclosed |
| US-9604897-B2 | Ionic liquid composition | RELIANCE INDUSTRIES LIMITED (IN) | 2017-03-28 | — | — | US | disclosed |
| US-20160107972-A1 | IONIC LIQUID COMPOSITION | RELIANCE INDUSTRIES LIMITED (IN) | 2016-04-21 | — | — | US | disclosed |
| EP-2997114-A2 | IONIC LIQUID COMPOSITION | Reliance Industries Limited (IN) | 2016-03-23 | — | — | EP | disclosed |
| WO-2014184804-A2 | IONIC LIQUID COMPOSITION | RELIANCE INDUSTRIES LIMITED (IN) | 2014-11-20 | — | — | WO | disclosed |
| CN-100425621-C | Steroid imidazole salt compound and its preparing process | UNIV YUNNAN (CN) | 2008-10-15 | — | — | CN | disclosed |
| CN-1876672-A | Steroid imidazole salt compound and its preparing process | UNIV YUNNAN (CN) | 2006-12-13 | — | — | CN | disclosed |