SCHEMBL22063900

SCHEMBL22063900

c1ccccc(Cn2ccnc2)cccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 16/20 1.00
CYP11B2 P19099 13/20 1.00
CYP19A1 P11511 6/20 1.00
CYP1A2 P05177 1/20 1.00
POLB P06746 1/20 1.00
CYP3A4 P08684 1/20 1.00
CYP2D6 P10635 1/20 1.00
MAPT P10636 1/20 1.00
TBXAS1 P24557 1/20 1.00
QPCT Q16769 1/20 1.00
CYP4Z1 Q86W10 1/20 1.00
QPCTL Q9NXS2 1/20 1.00
CYP17A1 P05093 1/20 0.79
CYP2A6 P11509 1/20 0.69
CYP2B6 P20813 1/20 0.69

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzylimidazole SCHEMBL414 1.00 CYP11B1 (1.00) CYP11B1CYP11B2CYP19A1CYP1A2POLB
Benzylimidazole SCHEMBL31453527 0.98 CYP11B1 (0.96) CYP11B1CYP11B2CYP19A1CYP1A2POLB
Benzylimidazole SCHEMBL29239318 0.98 CYP11B1 (0.96) CYP11B1CYP11B2CYP19A1CYP1A2POLB
Benzylimidazole SCHEMBL16237308 0.98 CYP11B1 (0.96) CYP11B1CYP11B2CYP19A1CYP1A2POLB
Benzylimidazole SCHEMBL3786782 0.98 CYP11B1 (0.96) CYP11B1CYP11B2CYP19A1CYP1A2POLB
Benzylimidazole SCHEMBL411827 0.98 CYP11B1 (0.96) CYP11B1CYP11B2CYP19A1CYP1A2POLB
Benzylimidazole SCHEMBL27803894 0.94 CYP11B1 (0.89) CYP11B1CYP11B2CYP19A1CYP1A2POLB
Benzylimidazole SCHEMBL28764644 0.93 CYP11B1 (0.86) CYP11B1CYP11B2CYP19A1CYP1A2POLB
Benzylimidazole SCHEMBL27535101 0.93 CYP11B1 (0.86) CYP11B1CYP11B2CYP19A1CYP1A2POLB
Benzylimidazole SCHEMBL28970402 0.91 CYP11B1 (0.83) CYP11B1CYP11B2CYP19A1CYP1A2POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10927100-B2 Degradable imidazolium oligomer and polymer for antimicrobial applications AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2021-02-23 US disclosed
US-20200181122-A1 Degradable Imidazolium Oligomer and Polymer for Antimicrobial Applications AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) 2020-06-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10927100-B2 Degradable imidazolium oligomer and polymer for antimicrobial applications NOD2, CFTR, PUF60 CYP11B1 3790/4885CYP11B2 3749/4885CYP19A1 4646/4885
US-20200181122-A1 Degradable Imidazolium Oligomer and Polymer for Antimicrobial Applications NOD2, CFTR, PUF60 CYP11B1 3790/4885CYP11B2 3749/4885CYP19A1 4646/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.