Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CDC25B | P30305 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25245488 | 0.87 | TSHR (0.39) | UCHL1TSHRLMNAMAPTHSD17B10 | |
| SCHEMBL12215764 | 0.85 | TSHR (0.50) | UCHL1TSHRMAPTHSD17B10ALDH1A1 | |
| SCHEMBL11662 | 0.85 | TSHR (0.57) | UCHL1TSHRLMNAMAPTHSD17B10 | |
| SCHEMBL29453753 | 0.85 | TSHR (0.57) | UCHL1TSHRLMNAMAPTHSD17B10 | |
| SCHEMBL12215759 | 0.83 | TSHR (0.47) | UCHL1TSHRLMNAMAPTHSD17B10 | |
| SCHEMBL16454773 | 0.82 | IDO1 (0.35) | UCHL1LMNAMAPTHSD17B10ALDH1A1 | |
| SCHEMBL29518411 | 0.82 | TSHR (0.46) | UCHL1TSHRMAPTHSD17B10ALDH1A1 | |
| SCHEMBL24378834 | 0.82 | TSHR (0.46) | UCHL1TSHRMAPTHSD17B10ALDH1A1 | |
| SCHEMBL23773427 | 0.79 | TSHR (0.68) | TSHRLMNAMAPTHSD17B10ALDH1A1 | |
| Benzoic Acid SCHEMBL22719459 | 0.79 | TSHR (0.49) | UCHL1TSHRLMNAMAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014186704-A2 | NOVEL COMPOUNDS FOR THE TREATMENT OF CYSTIC FIBROSIS | N30 PHARMACEUTICALS, INC. (US) | 2014-11-20 | — | — | WO | disclosed |