Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.47 |
| ▸ | CDC25B | P30305 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CDC25A | P30304 | 1/20 | 0.41 |
| ▸ | CDC25C | P30307 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11662 | 1.00 | TSHR (0.57) | TSHRALDH1A1HSD17B10UCHL1CDC25B | |
| Benzoic Acid SCHEMBL22719459 | 0.92 | TSHR (0.49) | TSHRALDH1A1HSD17B10UCHL1CDC25B | |
| SCHEMBL12215764 | 0.89 | TSHR (0.50) | TSHRALDH1A1HSD17B10UCHL1CDC25B | |
| SCHEMBL12215759 | 0.86 | TSHR (0.47) | TSHRALDH1A1HSD17B10UCHL1CDC25B | |
| SCHEMBL24378834 | 0.85 | TSHR (0.46) | TSHRALDH1A1HSD17B10UCHL1CDC25B | |
| SCHEMBL29518411 | 0.85 | TSHR (0.46) | TSHRALDH1A1HSD17B10UCHL1CDC25B | |
| SCHEMBL30353939 | 0.83 | TSHR (0.47) | TSHRALDH1A1HSD17B10UCHL1CDC25B | |
| SCHEMBL30509077 | 0.83 | ALDH1A1 (0.42) | TSHRALDH1A1HSD17B10UCHL1LMNA | |
| SCHEMBL29518456 | 0.83 | TSHR (0.47) | TSHRALDH1A1HSD17B10UCHL1CDC25B | |
| SCHEMBL24379045 | 0.83 | TSHR (0.47) | TSHRALDH1A1HSD17B10UCHL1CDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024071629-A1 | NOVEL FLUORENE DERIVATIVE COMPOUND AND USE THEREOF | (주)제이디바이오사이언스 | 2024-04-04 | — | — | WO | disclosed |
| EP-3976186-A1 | COMPOUNDS, COMPOSITIONS, AND METHODS OF USE | Sage Therapeutics, Inc. (US) | 2022-04-06 | — | — | EP | disclosed |