Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDO2 | P48775 | 16/20 | 0.93 |
| ▸ | IDO1 | P14902 | 4/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16247511 | 0.96 | TDO2 (1.00) | TDO2IDO1 | |
| SCHEMBL16247519 | 0.95 | TDO2 (0.82) | TDO2IDO1 | |
| SCHEMBL16237969 | 0.89 | TDO2 (1.00) | TDO2IDO1 | |
| SCHEMBL17503568 | 0.87 | TDO2 (0.82) | TDO2IDO1 | |
| SCHEMBL16237717 | 0.85 | TDO2 (0.75) | TDO2IDO1 | |
| SCHEMBL16247525 | 0.83 | TDO2 (1.00) | TDO2IDO1 | |
| SCHEMBL16247550 | 0.83 | TDO2 (0.74) | TDO2IDO1 | |
| SCHEMBL16247493 | 0.82 | IDO1 (0.68) | TDO2IDO1 | |
| SCHEMBL16247547 | 0.81 | TDO2 (0.72) | TDO2IDO1 | |
| SCHEMBL16247520 | 0.81 | TDO2 (0.83) | TDO2IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2970173-A1 | INHIBITORS OF THE KYNURENINE PATHWAY | Curadev Pharma Private Ltd. (IN) | 2016-01-20 | — | — | EP | claimed |
| WO-2014186035-A1 | INHIBITORS OF THE KYNURENINE PATHWAY | CURADEV PHARMA PRIVATE LTD. (IN) | 2014-11-20 | — | — | WO | claimed |