SCHEMBL16239089

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL16239021	0.87	SMN1; SMN2 (0.59)	P2RX4KMT2AMAPTTSHRALOX12
	SCHEMBL30094485	0.87	SMN1; SMN2 (0.59)	P2RX4KMT2AMAPTTSHRALOX12
	SCHEMBL18661904	0.86	P2RX4 (0.60)	P2RX4MAPTTSHRALOX12SMN1; SMN2
	SCHEMBL16239231	0.86	P2RX4 (0.50)	P2RX4KMT2AMAPTTSHRALOX12
	SCHEMBL2681057	0.86	P2RX4 (0.50)	P2RX4KMT2AMAPTTSHRALOX12
	SCHEMBL23094055	0.84	P2RX4 (0.50)	P2RX4KMT2AMAPTTSHRALOX12
	SCHEMBL2680321	0.83	P2RX4 (0.54)	P2RX4KMT2AGABRA1GABRA5GABRA3
	SCHEMBL2682170	0.81	P2RX4 (0.52)	P2RX4MAPTSMN1; SMN2GABRA1GABRA5
	SCHEMBL29984508	0.81	P2RX4 (0.49)	P2RX4KMT2AMAPTTSHRALOX12
	SCHEMBL25343785	0.80	P2RX4 (0.49)	P2RX4KMT2AMAPTTSHRALOX12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.