SCHEMBL1624312

SCHEMBL1624312

O=C(Oc1ccccc1)Oc1cc(OC(=O)Oc2ccccc2)cc(OC(=O)Oc2ccccc2)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.49
KMT2A Q03164 3/20 0.49
ALDH1A1 P00352 2/20 0.49
PPARG P37231 1/20 0.49
NCOA2 Q15596 1/20 0.49
NPSR1 Q6W5P4 1/20 0.49
RXFP1 Q9HBX9 1/20 0.49
NSD2 O96028 1/20 0.48
TDP1 Q9NUW8 2/20 0.48
ATM Q13315 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.48
MEN1 O00255 2/20 0.48
ALOX15 P16050 2/20 0.47
HPGD P15428 2/20 0.47
HSD17B10 Q99714 1/20 0.47
KDM4E B2RXH2 1/20 0.44
USP2 O75604 1/20 0.43
LMNA P02545 1/20 0.43
TP53 P04637 1/20 0.43
CYP3A4 P08684 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10596262 0.93 KMT2A (0.58) MAPTKMT2AALDH1A1PPARGNCOA2
SCHEMBL18073 0.92 TDP1 (0.54) MAPTKMT2AALDH1A1PPARGNCOA2
SCHEMBL27352197 0.92 TDP1 (0.54) MAPTKMT2AALDH1A1PPARGNCOA2
SCHEMBL9353461 0.92 TDP1 (0.54) MAPTKMT2AALDH1A1PPARGNCOA2
SCHEMBL9241160 0.92 TDP1 (0.54) MAPTKMT2AALDH1A1PPARGNCOA2
SCHEMBL9353455 0.92 TDP1 (0.54) MAPTKMT2AALDH1A1PPARGNCOA2
SCHEMBL1624304 0.90 KMT2A (0.52) MAPTKMT2AALDH1A1PPARGNCOA2
SCHEMBL8763081 0.90 TDP1 (0.52) MAPTKMT2AALDH1A1PPARGNCOA2
Bicarbonate SCHEMBL21879667 0.90 TDP1 (0.52) MAPTKMT2AALDH1A1PPARGNCOA2
SCHEMBL1362173 0.90 TDP1 (0.52) MAPTKMT2AALDH1A1PPARGNCOA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8507711-B2 Flame-retardant compound, flame-retardant particle, resin composition and resin formed body FUJI XEROX CO., LTD. (JP) 2013-08-13 US disclosed
US-8507711-B2 Flame-retardant compound, flame-retardant particle, resin composition and resin formed body FUJI XEROX CO., LTD. (JP) 2013-08-13 US disclosed
US-20120088871-A1 FLAME-RETARDANT COMPOUND, FLAME-RETARDANT PARTICLE, RESIN COMPOSITION AND RESIN FORMED BODY FUJI XEROX CO., LTD. (JP) 2012-04-12 US disclosed
US-20120088871-A1 FLAME-RETARDANT COMPOUND, FLAME-RETARDANT PARTICLE, RESIN COMPOSITION AND RESIN FORMED BODY FUJI XEROX CO., LTD. (JP) 2012-04-12 US disclosed
US-20090087659-A1 FLAME-RETARDANT COMPOUND, FLAME-RETARDANT PARTICLE, RESIN COMPOSITION AND RESIN FORMED BODY FUJI XEROX CO., LTD. (JP) 2009-04-02 US disclosed
US-20090087659-A1 FLAME-RETARDANT COMPOUND, FLAME-RETARDANT PARTICLE, RESIN COMPOSITION AND RESIN FORMED BODY FUJI XEROX CO., LTD. (JP) 2009-04-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090087659-A1 FLAME-RETARDANT COMPOUND, FLAME-RETARDANT PARTICLE, RESIN COMPOSITION AND RESIN FORMED BODY GAR1, RER1, AFF1 MAPT 2617/4885KMT2A 1265/4885ALDH1A1 537/4885
US-20120088871-A1 FLAME-RETARDANT COMPOUND, FLAME-RETARDANT PARTICLE, RESIN COMPOSITION AND RESIN FORMED BODY GAR1, RER1, RFT1 MAPT 3151/4885KMT2A 1046/4885ALDH1A1 993/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.