Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 10/20 | 0.55 |
| ▸ | DCPS | Q96C86 | 11/20 | 0.53 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.39 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.39 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.39 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.39 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.39 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.39 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.39 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16245272 | 1.00 | DHFR (0.55) | DHFRDCPSKCNH2CSNK1A1CSNK1D | |
| SCHEMBL14123376 | 0.85 | DHFR (0.54) | DHFRDCPSKCNH2CSNK1A1CSNK1D | |
| SCHEMBL1154661 | 0.83 | DHFR (0.59) | DHFRDCPSKCNH2CSNK1A1CSNK1D | |
| SCHEMBL1155046 | 0.83 | DHFR (0.59) | DHFRDCPSKCNH2CSNK1A1CSNK1D | |
| SCHEMBL1154672 | 0.83 | DHFR (0.59) | DHFRDCPSKCNH2CSNK1A1CSNK1D | |
| SCHEMBL14123319 | 0.81 | DHFR (0.59) | DHFRDCPSKCNH2CSNK1A1CSNK1D | |
| SCHEMBL14123413 | 0.81 | DHFR (0.59) | DHFRDCPSKCNH2CSNK1A1CSNK1D | |
| SCHEMBL1154559 | 0.78 | DHFR (0.61) | DHFRDCPSKCNH2 | |
| SCHEMBL1155243 | 0.78 | DHFR (0.75) | DHFRDCPSKCNH2CSNK1A1CSNK1D | |
| SCHEMBL1154543 | 0.78 | DHFR (0.75) | DHFRDCPSKCNH2CSNK1A1CSNK1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140349938-A1 | METHODS OF DIAGNOSING AND TREATING AMYOTROPHIC LATERAL SCLEROSIS | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2014-11-27 | — | — | US | disclosed |