Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.33 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | PDE8B | O95263 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29372042 | 0.98 | PDE10A (0.46) | PDE10ATDP1PDE4BPDE4DHCAR2 | |
| SCHEMBL287902 | 0.98 | PDE10A (0.46) | PDE10ATDP1PDE4BPDE4DHCAR2 | |
| Water SCHEMBL1581295 | 0.97 | PDE10A (0.45) | PDE10ATDP1PDE4BPDE4DHCAR2 | |
| SCHEMBL1535584 | 0.97 | PDE10A (0.45) | PDE10ATDP1PDE4BPDE4DHCAR2 | |
| Potassium Ion SCHEMBL3357867 | 0.82 | PDE10A (0.44) | PDE10APDE8B | |
| Potassium Ion SCHEMBL29409824 | 0.82 | PDE10A (0.44) | PDE10APDE8B | |
| SCHEMBL1535586 | 0.82 | PDE10A (0.47) | PDE10APDE8B | |
| SCHEMBL719516 | 0.81 | TDP1 (0.47) | PDE10ATDP1PDE4BPDE4DHCAR2 | |
| SCHEMBL121762 | 0.80 | PDE10A (0.49) | PDE10APDE4D | |
| SCHEMBL29615012 | 0.80 | PDE10A (0.49) | PDE10APDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9144240-B2 | Herbicidal pyrimidines | E I DU PONT DE NEMOURS AND COMPANY (US) | 2015-09-29 | — | — | US | claimed |
| US-20140350251-A1 | HERBICIDAL PYRIMIDINES | CORTEVA AGRISCIENCE LLC | 2014-11-27 | — | — | US | claimed |
| CN-106458958-A | Herbicidal propynyl-phenyl compounds | 先正达参股股份有限公司 | 2017-02-22 | — | — | CN | disclosed |
| CN-102264229-B | Herbicidal combination comprising dimethoxytriazinyl-substituted difluoromethanesulfonylanilines | BAYER CROPSCIENCE AG | 2013-10-30 | — | — | CN | disclosed |
| CN-102264229-A | Herbicidal combination comprising dimethoxytriazinyl-substituted difluoromethanesulfonylanilines | — | 2011-11-30 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140350251-A1 | HERBICIDAL PYRIMIDINES | CBR3, CBR1, DHODH | PDE10A 1993/4885TDP1 502/4885PDE4B 3673/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.