SCHEMBL287902

SCHEMBL287902

Nc1nc(C2CC2)nc(C(=O)O)c1Cl

nearest known ligand 0.46

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 2/20 0.46
TDP1 Q9NUW8 1/20 0.44
PDE4B Q07343 2/20 0.34
PDE4D Q08499 2/20 0.34
HCAR2 Q8TDS4 2/20 0.33
PDE8B O95263 2/20 0.33
IKBKE Q14164 1/20 0.30
TBK1 Q9UHD2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29372042 1.00 PDE10A (0.46) PDE10ATDP1PDE4BPDE4DHCAR2
Water SCHEMBL1581295 0.98 PDE10A (0.45) PDE10ATDP1PDE4BPDE4DHCAR2
SCHEMBL16245461 0.98 PDE10A (0.45) PDE10ATDP1PDE4BPDE4DHCAR2
SCHEMBL1535584 0.98 PDE10A (0.45) PDE10ATDP1PDE4BPDE4DHCAR2
Potassium Ion SCHEMBL3357867 0.83 PDE10A (0.44) PDE10APDE8B
SCHEMBL1535586 0.83 PDE10A (0.47) PDE10APDE8B
Potassium Ion SCHEMBL29409824 0.83 PDE10A (0.44) PDE10APDE8B
SCHEMBL719516 0.82 TDP1 (0.47) PDE10ATDP1PDE4BPDE4DHCAR2
SCHEMBL121762 0.81 PDE10A (0.49) PDE10APDE4D
SCHEMBL29615012 0.81 PDE10A (0.49) PDE10APDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 545 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260090545-A1 HERBICIDAL FORMULATIONS AND METHODS FOR THE TREATMENT OF DIFFICULT TO CONTROL WEED SPECIES DISCOVERY PURCHASER CORP (US) 2026-04-02 US claimed
US-20240397951-A1 HERBICIDAL MIXTURES MONSANTO TECHNOLOGY LLC 2024-12-05 US claimed
EP-4171224-A1 AUXIN HERBICIDE AND L-GLUFOSINATE MIXTURES Monsanto Technology LLC (US) 2023-05-03 EP claimed
US-20230072162-A1 AUXIN HERBICIDAL MIXTURES MONSANTO TECHNOLOGY LLC 2023-03-09 US claimed
CN-115349524-A Herbicidal mixtures 孟山都技术有限公司 2022-11-18 CN claimed
US-11452290-B2 Auxin herbicidal mixtures MONSANTO TECHNOLOGY LLC (US) 2022-09-27 US claimed
WO-2022005906-A1 AUXIN HERBICIDE AND L-GLUFOSINATE MIXTURES MONSANTO TECHNOLOGY LLC (US) 2022-01-06 WO claimed
US-20210400957-A1 AUXIN HERBICIDE AND L-GLUFOSINATE MIXTURES MONSANTO TECHNOLOGY LLC 2021-12-30 US claimed
EP-3731635-A1 HERBICIDAL MIXTURES Monsanto Technology LLC (US) 2020-11-04 EP claimed
CN-111770683-A Herbicidal mixtures 孟山都技术有限公司 2020-10-13 CN claimed
US-20100137139-A1 HERBICIDE/SAFENER COMBINATION BAYER CROPSCIENCE AG (DE) 2010-06-03 US claimed
WO-2010060578-A2 HERBICIDE/SAFENER COMBINATION BAYER CROPSCIENCE AG (DE) 2010-06-03 WO claimed
EP-2191720-A1 Herbicide-safener combination Bayer CropScience AG (DE) 2010-06-02 EP claimed
US-20090247404-A1 METHOD FOR IMPROVING HARVESTABILITY OF CROPS ANGIOTECH PHARMACEUTICALS, INC. (CA) 2009-10-01 US claimed
CN-101420852-A Herbicidal mixtures DU PONT (US) 2009-04-29 CN claimed
EP-2003972-A2 HERBICIDAL MIXTURES E.I. DU PONT DE NEMOURS AND COMPANY (US) 2008-12-24 EP claimed
WO-2008073369-A1 HERBICIDAL MIXTURES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2008-06-19 WO claimed
WO-2007120706-A2 HERBICIDAL MIXTURES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-10-25 WO claimed
WO-2007092184-A2 METHOD FOR IMPROVING HARVESTABILITY OF CROPS E. I. DU PONT DE NEMOURS AND COMPANY (US) 2007-08-16 WO claimed
CN-1894220-A Herbicidal pyrimidines DU PONT (US) 2007-01-10 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210400957-A1 AUXIN HERBICIDE AND L-GLUFOSINATE MIXTURES GLUL, PIK3C3, AGXT PDE10A 1951/4885TDP1 392/4885PDE4B 1275/4885
US-20090247404-A1 METHOD FOR IMPROVING HARVESTABILITY OF CROPS AMY1A, DDT, ACHE PDE10A 783/4885TDP1 222/4885PDE4B 320/4885
US-20260090545-A1 HERBICIDAL FORMULATIONS AND METHODS FOR THE TREATMENT OF DIFFICULT TO CONTROL WEED SPECIES CYP2U1, WEE2, CYP2W1 PDE10A 1337/4885TDP1 1458/4885PDE4B 1791/4885
US-20230072162-A1 AUXIN HERBICIDAL MIXTURES AS3MT, DDT, CDC25C PDE10A 2149/4885TDP1 2319/4885PDE4B 2630/4885
US-11452290-B2 Auxin herbicidal mixtures AS3MT, DDT, CDC25C PDE10A 2149/4885TDP1 2319/4885PDE4B 2630/4885
US-20240397951-A1 HERBICIDAL MIXTURES DDT, GMNN, AGXT PDE10A 2321/4885TDP1 1078/4885PDE4B 1679/4885
US-20100137139-A1 HERBICIDE/SAFENER COMBINATION CYP2W1, DDT, CBR3 PDE10A 2451/4885TDP1 803/4885PDE4B 2518/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.