Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | IL2 | P60568 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL471881 | 0.88 | KDM4E (0.62) | KDM4EHRH3MAPTLMNAHTT | |
| SCHEMBL11493291 | 0.87 | KDM4E (0.48) | KDM4EHRH3MAPTLMNAHTT | |
| SCHEMBL20410843 | 0.85 | KDM4E (0.59) | KDM4EHRH3MAPTLMNAHTT | |
| SCHEMBL30863841 | 0.82 | KDM4E (0.56) | KDM4EHRH3MAPTLMNAHTT | |
| SCHEMBL1338857 | 0.82 | KDM4E (0.56) | KDM4EHRH3MAPTLMNAHTT | |
| SCHEMBL4027768 | 0.81 | LMNA (0.48) | KDM4EHRH3MAPTLMNAHTT | |
| SCHEMBL20410959 | 0.81 | KDM4E (0.58) | KDM4EHRH3MAPTLMNAHTT | |
| SCHEMBL20410735 | 0.81 | KDM4E (0.54) | KDM4EHRH3MAPTLMNAHTT | |
| SCHEMBL8491691 | 0.81 | HPGD (0.55) | KDM4EHRH3MAPTLMNAHTT | |
| SCHEMBL3750225 | 0.81 | KDM4E (0.54) | KDM4EHRH3MAPTLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021262548-A1 | A PLATFORM FOR SCREENING NAD+ BINDING PROTEINS IN A CELLULAR CONTEXT | OREGON HEALTH & SCIENCE UNIVERSITY (US) | 2021-12-30 | — | — | WO | disclosed |
| US-20170066717-A1 | NEW PHENYLAZETIDINECARBOXYLATE OR -CARBOXAMIDE COMPOUNDS | INVENTIVA (FR) | 2017-03-09 | — | — | US | disclosed |
| EP-3107910-A1 | NEW PHENYLAZETIDINE, CARBOXYLATE OR CARBOXAMIDE COMPOUNDS | INVENTIVA (FR) | 2016-12-28 | — | — | EP | disclosed |
| WO-2015124868-A1 | NEW PHENYLAZETIDINE, CARBOXYLATE OR CARBOXAMIDE COMPOUNDS | INVENTIVA (FR) | 2015-08-27 | — | — | WO | disclosed |
| US-7928129-B1 | Nanomolar β-lactamase inhibitors | NORTHWESTERN UNIVERSITY (US) | 2011-04-19 | — | — | US | disclosed |
| US-7928129-B1 | Nanomolar β-lactamase inhibitors | NORTHWESTERN UNIVERSITY (US) | 2011-04-19 | — | — | US | disclosed |
| US-7928129-B1 | Nanomolar β-lactamase inhibitors | NORTHWESTERN UNIVERSITY (US) | 2011-04-19 | — | — | US | disclosed |
| US-20070265256-A1 | Phosphodiesterase 10 inhibitors | AMGEN INC. | 2007-11-15 | — | — | US | disclosed |
| US-20070265256-A1 | Phosphodiesterase 10 inhibitors | AMGEN INC. | 2007-11-15 | — | — | US | disclosed |
| US-7271186-B1 | Nanomolar β-lactamase inhibitors | NORTHWESTERN UNIVERSITY (US) | 2007-09-18 | — | — | US | disclosed |
| EP-0063374-B1 | SUBSTITUTED BIPHENYL COMPOUNDS | FMC Corporation (US) | 1984-02-22 | — | — | EP | disclosed |
| US-4402973-A | Insecticidal (1,1'-biphenyl)-3-ylmethyl esters | FMC CORPORATION (US) | 1983-09-06 | — | — | US | disclosed |
| EP-0020685-B1 | INSECTICIDAL CYCLOPROPANECARBOXYLATES FROM SUBSTITUTED (1,1'-BIPHENYL)-3-YLMETHYL COMPOUNDS | FMC Corporation (US) | 1983-06-15 | — | — | EP | disclosed |
| EP-0063374-A1 | Substituted biphenyl compounds | FMC Corporation (US) | 1982-10-27 | — | — | EP | disclosed |
| US-4329518-A | INSECTICIDES, ACARICIDES, MITICIDES | FMC CORPORATION (US) | 1982-05-11 | — | — | US | disclosed |
| EP-0049977-A1 | Insecticidal (1,1'-biphenyl)-3-ylmethyl esters, their production and use and compositions containing them | FMC Corporation (US) | 1982-04-21 | — | — | EP | disclosed |
| EP-0020685-A4 | INSECTICIDAL CYCLOPROPANECARBOXYLATES FROM SUBSTITUTED (1,1'-BIPHENYL)-3-YLMETHYL COMPOUNDS. | FMC CORP (US) | 1981-07-16 | — | — | EP | disclosed |
| EP-0020685-A1 | INSECTICIDAL CYCLOPROPANECARBOXYLATES FROM SUBSTITUTED (1,1'-BIPHENYL)-3-YLMETHYL COMPOUNDS. | FMC CORP (US) | 1981-01-07 | — | — | EP | disclosed |
| US-4214004-A | MITICIDES | FMC CORPORATION (US) | 1980-07-22 | — | — | US | disclosed |
| WO-1980001163-A1 | INSECTICIDAL CYCLOPROPANECARBOXYLATES FROM SUBSTITUTED(1,1'-BIPHENYL)-3-YLMETHYL COMPOUNDS | FMC CORP (US) | 1980-06-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170066717-A1 | NEW PHENYLAZETIDINECARBOXYLATE OR -CARBOXAMIDE COMPOUNDS | NCOR1, NCOR2, NCOA1 | KDM4E 517/4885HRH3 541/4885MAPT 2804/4885 |
| US-20070265256-A1 | Phosphodiesterase 10 inhibitors | PDE7A, PDE7B, PDE10A | KDM4E 2328/4885HRH3 4562/4885MAPT 3278/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.